Jahn-Hofmann K - Search Results

1

Delivery of siRNA to the mouse lung via a functionalized lipopolyamine.

Polach KJ, Matar M, Rice J, Slobodkin G, Sparks J, Congo R, Rea-Ramsey A, McClure D, Brunhoeber E, Krampert M, Schuster A, Jahn-Hofmann K, John M, Vornlocher HP, Fewell JG, Anwer K, Geick A. Polach KJ, et al. Mol Ther. 2012 Jan;20(1):91-100. doi: 10.1038/mt.2011.210. Epub 2011 Oct 11. Mol Ther. 2012. PMID: 21988874 Free PMC article.

2

Hepatocyte-targeted RNAi therapeutics for the treatment of chronic hepatitis B virus infection.

Wooddell CI, Rozema DB, Hossbach M, John M, Hamilton HL, Chu Q, Hegge JO, Klein JJ, Wakefield DH, Oropeza CE, Deckert J, Roehl I, Jahn-Hofmann K, Hadwiger P, Vornlocher HP, McLachlan A, Lewis DL. Wooddell CI, et al. Mol Ther. 2013 May;21(5):973-85. doi: 10.1038/mt.2013.31. Epub 2013 Feb 26. Mol Ther. 2013. PMID: 23439496 Free PMC article.

3

Characterization of side reactions during the annealing of small interfering RNAs.

Seiffert S, Debelak H, Hadwiger P, Jahn-Hofmann K, Roehl I, Vornlocher HP, Noll B. Seiffert S, et al. Anal Biochem. 2011 Jul 1;414(1):47-57. doi: 10.1016/j.ab.2011.02.040. Epub 2011 Mar 2. Anal Biochem. 2011. PMID: 21376008

4

Chemical modifications on siRNAs avoid Toll-like-receptor-mediated activation of the hepatic immune system in vivo and in vitro.

Broering R, Real CI, John MJ, Jahn-Hofmann K, Ickenstein LM, Kleinehr K, Paul A, Gibbert K, Dittmer U, Gerken G, Schlaak JF. Broering R, et al. Int Immunol. 2014 Jan;26(1):35-46. doi: 10.1093/intimm/dxt040. Epub 2013 Sep 24. Int Immunol. 2014. PMID: 24065781

5

Targeted siRNA Delivery and mRNA Knockdown Mediated by Bispecific Digoxigenin-binding Antibodies.

Schneider B, Grote M, John M, Haas A, Bramlage B, Ickenstein LM, Jahn-Hofmann K, Bauss F, Cheng W, Croasdale R, Daub K, Dill S, Hoffmann E, Lau W, Burtscher H, Ludtke JL, Metz S, Mundigl O, Neal ZC, Scheuer W, Stracke J, Herweijer H, Brinkmann U. Schneider B, et al. Mol Ther Nucleic Acids. 2012 Sep 18;1(9):e46. doi: 10.1038/mtna.2012.39. Mol Ther Nucleic Acids. 2012. PMID: 23344238 Free PMC article.

6

Hepatitis B virus genome replication triggers toll-like receptor 3-dependent interferon responses in the absence of hepatitis B surface antigen.

Real CI, Lu M, Liu J, Huang X, Trippler M, Hossbach M, Deckert J, Jahn-Hofmann K, Ickenstein LM, John MJ, Gibbert K, Dittmer U, Vornlocher HP, Schirmbeck R, Gerken G, Schlaak JF, Broering R. Real CI, et al. Sci Rep. 2016 Apr 28;6:24865. doi: 10.1038/srep24865. Sci Rep. 2016. PMID: 27121087 Free PMC article.

7

Host scavenger receptor SR-BI plays a dual role in the establishment of malaria parasite liver infection.

Rodrigues CD, Hannus M, Prudêncio M, Martin C, Gonçalves LA, Portugal S, Epiphanio S, Akinc A, Hadwiger P, Jahn-Hofmann K, Röhl I, van Gemert GJ, Franetich JF, Luty AJ, Sauerwein R, Mazier D, Koteliansky V, Vornlocher HP, Echeverri CJ, Mota MM. Rodrigues CD, et al. Cell Host Microbe. 2008 Sep 11;4(3):271-82. doi: 10.1016/j.chom.2008.07.012. Cell Host Microbe. 2008. PMID: 18779053 Free article.

8

Nanobody-siRNA Conjugates for Targeted Delivery of siRNA to Cancer Cells.

Zavoiura O, Brunner B, Casteels P, Zimmermann L, Ozog M, Boutton C, Helms MW, Wagenaar T, Adam V, Peterka J, Metz-Weidmann C, Deschaght P, Scheidler S, Jahn-Hofmann K. Zavoiura O, et al. Among authors: jahn hofmann k. Mol Pharm. 2021 Mar 1;18(3):1048-1060. doi: 10.1021/acs.molpharmaceut.0c01001. Epub 2021 Jan 14. Mol Pharm. 2021. PMID: 33444501

9

Identification of proteins that mediate the pro-viral functions of the interferon stimulated gene 15 in hepatitis C virus replication.

Real CI, Megger DA, Sitek B, Jahn-Hofmann K, Ickenstein LM, John MJ, Walker A, Timm J, Kuhlmann K, Eisenacher M, Meyer HE, Gerken G, Broering R, Schlaak JF. Real CI, et al. Antiviral Res. 2013 Dec;100(3):654-61. doi: 10.1016/j.antiviral.2013.10.009. Antiviral Res. 2013. PMID: 24416772

10

Conformational rearrangements of RIG-I receptor on formation of a multiprotein:dsRNA assembly.

Beckham SA, Brouwer J, Roth A, Wang D, Sadler AJ, John M, Jahn-Hofmann K, Williams BR, Wilce JA, Wilce MC. Beckham SA, et al. Nucleic Acids Res. 2013 Mar 1;41(5):3436-45. doi: 10.1093/nar/gks1477. Epub 2013 Jan 15. Nucleic Acids Res. 2013. PMID: 23325848 Free PMC article.

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