Pawson T - Search Results

1

Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis.

Grebien F, Hantschel O, Wojcik J, Kaupe I, Kovacic B, Wyrzucki AM, Gish GD, Cerny-Reiterer S, Koide A, Beug H, Pawson T, Valent P, Koide S, Superti-Furga G. Grebien F, et al. Among authors: pawson t. Cell. 2011 Oct 14;147(2):306-19. doi: 10.1016/j.cell.2011.08.046. Cell. 2011. PMID: 22000011 Free PMC article.

2

Structural coupling of SH2-kinase domains links Fes and Abl substrate recognition and kinase activation.

Filippakopoulos P, Kofler M, Hantschel O, Gish GD, Grebien F, Salah E, Neudecker P, Kay LE, Turk BE, Superti-Furga G, Pawson T, Knapp S. Filippakopoulos P, et al. Among authors: pawson t. Cell. 2008 Sep 5;134(5):793-803. doi: 10.1016/j.cell.2008.07.047. Cell. 2008. PMID: 18775312 Free PMC article.

3

SH2 and SH3 domains: from structure to function.

Pawson T, Gish GD. Pawson T, et al. Cell. 1992 Oct 30;71(3):359-62. doi: 10.1016/0092-8674(92)90504-6. Cell. 1992. PMID: 1423600 Review. No abstract available.

4

Directed network wiring identifies a key protein interaction in embryonic stem cell differentiation.

Yasui N, Findlay GM, Gish GD, Hsiung MS, Huang J, Tucholska M, Taylor L, Smith L, Boldridge WC, Koide A, Pawson T, Koide S. Yasui N, et al. Among authors: pawson t. Mol Cell. 2014 Jun 19;54(6):1034-1041. doi: 10.1016/j.molcel.2014.05.002. Epub 2014 Jun 5. Mol Cell. 2014. PMID: 24910098 Free PMC article.

5

Structure of a regulatory complex involving the Abl SH3 domain, the Crk SH2 domain, and a Crk-derived phosphopeptide.

Donaldson LW, Gish G, Pawson T, Kay LE, Forman-Kay JD. Donaldson LW, et al. Among authors: pawson t. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14053-8. doi: 10.1073/pnas.212518799. Epub 2002 Oct 16. Proc Natl Acad Sci U S A. 2002. PMID: 12384576 Free PMC article.

6

The discoidin domain receptor tyrosine kinases are activated by collagen.

Vogel W, Gish GD, Alves F, Pawson T. Vogel W, et al. Among authors: pawson t. Mol Cell. 1997 Dec;1(1):13-23. doi: 10.1016/s1097-2765(00)80003-9. Mol Cell. 1997. PMID: 9659899 Free article.

7

Structural basis for specificity switching of the Src SH2 domain.

Kimber MS, Nachman J, Cunningham AM, Gish GD, Pawson T, Pai EF. Kimber MS, et al. Among authors: pawson t. Mol Cell. 2000 Jun;5(6):1043-9. doi: 10.1016/s1097-2765(00)80269-5. Mol Cell. 2000. PMID: 10911998 Free article.

8

SH2 domains, interaction modules and cellular wiring.

Pawson T, Gish GD, Nash P. Pawson T, et al. Trends Cell Biol. 2001 Dec;11(12):504-11. doi: 10.1016/s0962-8924(01)02154-7. Trends Cell Biol. 2001. PMID: 11719057 Review.

9

SH2 domains recognize specific phosphopeptide sequences.

Songyang Z, Shoelson SE, Chaudhuri M, Gish G, Pawson T, Haser WG, King F, Roberts T, Ratnofsky S, Lechleider RJ, et al. Songyang Z, et al. Among authors: pawson t. Cell. 1993 Mar 12;72(5):767-78. doi: 10.1016/0092-8674(93)90404-e. Cell. 1993. PMID: 7680959

10

A potential SH3 domain-binding site in the Crk SH2 domain.

Anafi M, Rosen MK, Gish GD, Kay LE, Pawson T. Anafi M, et al. Among authors: pawson t. J Biol Chem. 1996 Aug 30;271(35):21365-74. doi: 10.1074/jbc.271.35.21365. J Biol Chem. 1996. PMID: 8702917 Free article.

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