Groessl M - Search Results

1

Maleimide-functionalised organoruthenium anticancer agents and their binding to thiol-containing biomolecules.

Hanif M, Nazarov AA, Legin A, Groessl M, Arion VB, Jakupec MA, Tsybin YO, Dyson PJ, Keppler BK, Hartinger CG. Hanif M, et al. Among authors: groessl m. Chem Commun (Camb). 2012 Feb 1;48(10):1475-7. doi: 10.1039/c1cc14713g. Epub 2011 Oct 14. Chem Commun (Camb). 2012. PMID: 22003496

2

Elucidation of the interactions of an anticancer ruthenium complex in clinical trials with biomolecules utilizing capillary electrophoresis hyphenated to inductively coupled plasma-mass spectrometry. Short communication.

Groessl M, Hartinger CG, Połeć-Pawlak K, Jarosz M, Dyson PJ, Keppler BK. Groessl M, et al. Chem Biodivers. 2008 Aug;5(8):1609-1614. doi: 10.1002/cbdv.200890148. Chem Biodivers. 2008. PMID: 18729095

3

Transferring the concept of multinuclearity to ruthenium complexes for improvement of anticancer activity.

Mendoza-Ferri MG, Hartinger CG, Mendoza MA, Groessl M, Egger AE, Eichinger RE, Mangrum JB, Farrell NP, Maruszak M, Bednarski PJ, Klein F, Jakupec MA, Nazarov AA, Severin K, Keppler BK. Mendoza-Ferri MG, et al. Among authors: groessl m. J Med Chem. 2009 Feb 26;52(4):916-25. doi: 10.1021/jm8013234. J Med Chem. 2009. PMID: 19170599 Free PMC article.

4

Ligand substitutions between ruthenium-cymene compounds can control protein versus DNA targeting and anticancer activity.

Adhireksan Z, Davey GE, Campomanes P, Groessl M, Clavel CM, Yu H, Nazarov AA, Yeo CH, Ang WH, Dröge P, Rothlisberger U, Dyson PJ, Davey CA. Adhireksan Z, et al. Among authors: groessl m. Nat Commun. 2014 Mar 18;5:3462. doi: 10.1038/ncomms4462. Nat Commun. 2014. PMID: 24637564 Free PMC article.

5

A glucose derivative as natural alternative to the cyclohexane-1,2-diamine ligand in the anticancer drug oxaliplatin?

Berger I, Nazarov AA, Hartinger CG, Groessl M, Valiahdi SM, Jakupec MA, Keppler BK. Berger I, et al. Among authors: groessl m. ChemMedChem. 2007 Apr;2(4):505-14. doi: 10.1002/cmdc.200600279. ChemMedChem. 2007. PMID: 17340670

6

Structure-activity relationships for NAMI-A-type complexes (HL)[trans-RuCl4L(S-dmso)ruthenate(III)] (L = imidazole, indazole, 1,2,4-triazole, 4-amino-1,2,4-triazole, and 1-methyl-1,2,4-triazole): aquation, redox properties, protein binding, and antiproliferative activity.

Groessl M, Reisner E, Hartinger CG, Eichinger R, Semenova O, Timerbaev AR, Jakupec MA, Arion VB, Keppler BK. Groessl M, et al. J Med Chem. 2007 May 3;50(9):2185-93. doi: 10.1021/jm061081y. Epub 2007 Apr 3. J Med Chem. 2007. PMID: 17402720

7

CZE-ICP-MS as a tool for studying the hydrolysis of ruthenium anticancer drug candidates and their reactivity towards the DNA model compound dGMP.

Groessl M, Hartinger CG, Dyson PJ, Keppler BK. Groessl M, et al. J Inorg Biochem. 2008 May-Jun;102(5-6):1060-5. doi: 10.1016/j.jinorgbio.2007.11.018. Epub 2007 Dec 14. J Inorg Biochem. 2008. PMID: 18222004

8

Capillary electrophoresis hyphenated to inductively coupled plasma-mass spectrometry: a novel approach for the analysis of anticancer metallodrugs in human serum and plasma.

Groessl M, Hartinger CG, Polec-Pawlak K, Jarosz M, Keppler BK. Groessl M, et al. Electrophoresis. 2008 May;29(10):2224-32. doi: 10.1002/elps.200780790. Electrophoresis. 2008. PMID: 18512673 Clinical Trial.

9

In vitro anticancer activity and biologically relevant metabolization of organometallic ruthenium complexes with carbohydrate-based ligands.

Berger I, Hanif M, Nazarov AA, Hartinger CG, John RO, Kuznetsov ML, Groessl M, Schmitt F, Zava O, Biba F, Arion VB, Galanski M, Jakupec MA, Juillerat-Jeanneret L, Dyson PJ, Keppler BK. Berger I, et al. Among authors: groessl m. Chemistry. 2008;14(29):9046-9057. doi: 10.1002/chem.200801032. Chemistry. 2008. PMID: 18688905

10

KP1019, a new redox-active anticancer agent--preclinical development and results of a clinical phase I study in tumor patients.

Hartinger CG, Jakupec MA, Zorbas-Seifried S, Groessl M, Egger A, Berger W, Zorbas H, Dyson PJ, Keppler BK. Hartinger CG, et al. Among authors: groessl m. Chem Biodivers. 2008 Oct;5(10):2140-2155. doi: 10.1002/cbdv.200890195. Chem Biodivers. 2008. PMID: 18972504 Review.

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