Vischer HF - Search Results

1

Molecular determinants of ligand binding modes in the histamine H(4) receptor: linking ligand-based three-dimensional quantitative structure-activity relationship (3D-QSAR) models to in silico guided receptor mutagenesis studies.

Istyastono EP, Nijmeijer S, Lim HD, van de Stolpe A, Roumen L, Kooistra AJ, Vischer HF, de Esch IJ, Leurs R, de Graaf C. Istyastono EP, et al. Among authors: vischer hf. J Med Chem. 2011 Dec 8;54(23):8136-47. doi: 10.1021/jm201042n. Epub 2011 Nov 7. J Med Chem. 2011. PMID: 22003888

2

Receptor mutagenesis strategies for examination of structure-function relationships.

Blomenröhr M, Vischer HF, Bogerd J. Blomenröhr M, et al. Among authors: vischer hf. Methods Mol Biol. 2004;259:307-22. doi: 10.1385/1-59259-754-8:307. Methods Mol Biol. 2004. PMID: 15250501

3

CC and CX3C chemokines differentially interact with the N terminus of the human cytomegalovirus-encoded US28 receptor.

Casarosa P, Waldhoer M, LiWang PJ, Vischer HF, Kledal T, Timmerman H, Schwartz TW, Smit MJ, Leurs R. Casarosa P, et al. Among authors: vischer hf. J Biol Chem. 2005 Feb 4;280(5):3275-85. doi: 10.1074/jbc.M407536200. Epub 2004 Nov 16. J Biol Chem. 2005. PMID: 15546882 Free article.

4

Chemokine-directed trafficking of receptor stimulus to different g proteins: selective inducible and constitutive signaling by human herpesvirus 6-encoded chemokine receptor U51.

Fitzsimons CP, Gompels UA, Verzijl D, Vischer HF, Mattick C, Leurs R, Smit MJ. Fitzsimons CP, et al. Among authors: vischer hf. Mol Pharmacol. 2006 Mar;69(3):888-98. doi: 10.1124/mol.105.015222. Epub 2005 Dec 6. Mol Pharmacol. 2006. PMID: 16332987

5

HCMV-encoded G-protein-coupled receptors as constitutively active modulators of cellular signaling networks.

Vischer HF, Leurs R, Smit MJ. Vischer HF, et al. Trends Pharmacol Sci. 2006 Jan;27(1):56-63. doi: 10.1016/j.tips.2005.11.006. Epub 2005 Dec 13. Trends Pharmacol Sci. 2006. PMID: 16352349 Review.

6

Synthesis and pharmacological characterization of novel inverse agonists acting on the viral-encoded chemokine receptor US28.

Hulshof JW, Vischer HF, Verheij MH, Fratantoni SA, Smit MJ, de Esch IJ, Leurs R. Hulshof JW, et al. Among authors: vischer hf. Bioorg Med Chem. 2006 Nov 1;14(21):7213-30. doi: 10.1016/j.bmc.2006.06.054. Epub 2006 Jul 14. Bioorg Med Chem. 2006. PMID: 16843661

7

Pharmacogenomic and structural analysis of constitutive g protein-coupled receptor activity.

Smit MJ, Vischer HF, Bakker RA, Jongejan A, Timmerman H, Pardo L, Leurs R. Smit MJ, et al. Among authors: vischer hf. Annu Rev Pharmacol Toxicol. 2007;47:53-87. doi: 10.1146/annurev.pharmtox.47.120505.105126. Annu Rev Pharmacol Toxicol. 2007. PMID: 17029567 Free article. Review.

8

Virus-encoded G-protein-coupled receptors: constitutively active (dys)regulators of cell function and their potential as drug target.

Vischer HF, Hulshof JW, de Esch IJ, Smit MJ, Leurs R. Vischer HF, et al. Ernst Schering Found Symp Proc. 2006;(2):187-209. doi: 10.1007/2789_2006_009. Ernst Schering Found Symp Proc. 2006. PMID: 17703583 Review.

9

Viral hijacking of human receptors through heterodimerization.

Vischer HF, Nijmeijer S, Smit MJ, Leurs R. Vischer HF, et al. Biochem Biophys Res Commun. 2008 Dec 5;377(1):93-7. doi: 10.1016/j.bbrc.2008.09.082. Epub 2008 Sep 26. Biochem Biophys Res Commun. 2008. PMID: 18823943

10

Herpesvirus-encoded G protein-coupled receptors as modulators of cellular function.

Maussang D, Vischer HF, Leurs R, Smit MJ. Maussang D, et al. Among authors: vischer hf. Mol Pharmacol. 2009 Oct;76(4):692-701. doi: 10.1124/mol.109.057091. Epub 2009 Jul 1. Mol Pharmacol. 2009. PMID: 19570946 Review.

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