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Iron deficiency drives an autosomal dominant hypophosphatemic rickets (ADHR) phenotype in fibroblast growth factor-23 (Fgf23) knock-in mice.
Farrow EG, Yu X, Summers LJ, Davis SI, Fleet JC, Allen MR, Robling AG, Stayrook KR, Jideonwo V, Magers MJ, Garringer HJ, Vidal R, Chan RJ, Goodwin CB, Hui SL, Peacock M, White KE. Farrow EG, et al. Among authors: chan rj. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):E1146-55. doi: 10.1073/pnas.1110905108. Epub 2011 Oct 17. Proc Natl Acad Sci U S A. 2011. PMID: 22006328 Free PMC article.
Systemic and cerebral iron homeostasis in ferritin knock-out mice.
Li W, Garringer HJ, Goodwin CB, Richine B, Acton A, VanDuyn N, Muhoberac BB, Irimia-Dominguez J, Chan RJ, Peacock M, Nass R, Ghetti B, Vidal R. Li W, et al. Among authors: chan rj. PLoS One. 2015 Jan 28;10(1):e0117435. doi: 10.1371/journal.pone.0117435. eCollection 2015. PLoS One. 2015. PMID: 25629408 Free PMC article.
Erythropoietin stimulates murine and human fibroblast growth factor-23, revealing novel roles for bone and bone marrow.
Clinkenbeard EL, Hanudel MR, Stayrook KR, Appaiah HN, Farrow EG, Cass TA, Summers LJ, Ip CS, Hum JM, Thomas JC, Ivan M, Richine BM, Chan RJ, Clemens TL, Schipani E, Sabbagh Y, Xu L, Srour EF, Alvarez MB, Kacena MA, Salusky IB, Ganz T, Nemeth E, White KE. Clinkenbeard EL, et al. Among authors: chan rj. Haematologica. 2017 Nov;102(11):e427-e430. doi: 10.3324/haematol.2017.167882. Epub 2017 Aug 17. Haematologica. 2017. PMID: 28818868 Free PMC article. No abstract available.
Rho kinase regulates the survival and transformation of cells bearing oncogenic forms of KIT, FLT3, and BCR-ABL.
Mali RS, Ramdas B, Ma P, Shi J, Munugalavadla V, Sims E, Wei L, Vemula S, Nabinger SC, Goodwin CB, Chan RJ, Traina F, Visconte V, Tiu RV, Lewis TA, Stern AM, Wen Q, Crispino JD, Boswell HS, Kapur R. Mali RS, et al. Among authors: chan rj. Cancer Cell. 2011 Sep 13;20(3):357-69. doi: 10.1016/j.ccr.2011.07.016. Cancer Cell. 2011. PMID: 21907926 Free PMC article.
Inhibition of BTK and PI3Kδ impairs the development of human JMML stem and progenitor cells.
Ramdas B, Yuen LD, Palam LR, Patel R, Pasupuleti SK, Jideonwo V, Zhang J, Maguire C, Wong E, Kanumuri R, Zhang C, Sandusky G, Chan RJ, Zhang C, Stieglitz E, Haneline L, Kapur R. Ramdas B, et al. Among authors: chan rj. Mol Ther. 2022 Jul 6;30(7):2505-2521. doi: 10.1016/j.ymthe.2022.04.009. Epub 2022 Apr 20. Mol Ther. 2022. PMID: 35443935 Free PMC article.
311 results