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A novel nonsense variant in Nav1.5 cofactor MOG1 eliminates its sodium current increasing effect and may increase the risk of arrhythmias.
Olesen MS, Jensen NF, Holst AG, Nielsen JB, Tfelt-Hansen J, Jespersen T, Sajadieh A, Haunsø S, Lund JT, Calloe K, Schmitt N, Svendsen JH. Olesen MS, et al. Among authors: schmitt n. Can J Cardiol. 2011 Jul-Aug;27(4):523.e17-23. doi: 10.1016/j.cjca.2011.01.003. Epub 2011 May 28. Can J Cardiol. 2011. PMID: 21621375 English, French.
Brugada syndrome risk loci seem protective against atrial fibrillation.
Andreasen L, Nielsen JB, Darkner S, Christophersen IE, Jabbari J, Refsgaard L, Thiis JJ, Sajadieh A, Tveit A, Haunsø S, Svendsen JH, Schmitt N, Olesen MS. Andreasen L, et al. Among authors: schmitt n. Eur J Hum Genet. 2014 Dec;22(12):1357-61. doi: 10.1038/ejhg.2014.46. Epub 2014 Mar 26. Eur J Hum Genet. 2014. PMID: 24667784 Free PMC article.
Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada syndrome mutant.
Yuan L, Koivumäki JT, Liang B, Lorentzen LG, Tang C, Andersen MN, Svendsen JH, Tfelt-Hansen J, Maleckar M, Schmitt N, Olesen MS, Jespersen T. Yuan L, et al. Among authors: schmitt n. Am J Physiol Heart Circ Physiol. 2014 Apr 15;306(8):H1204-12. doi: 10.1152/ajpheart.00405.2013. Epub 2014 Feb 21. Am J Physiol Heart Circ Physiol. 2014. PMID: 24561865 Free article.
413 results