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Endogenous Production of IL1B by Breast Cancer Cells Drives Metastasis and Colonization of the Bone Microenvironment.
Tulotta C, Lefley DV, Freeman K, Gregory WM, Hanby AM, Heath PR, Nutter F, Wilkinson JM, Spicer-Hadlington AR, Liu X, Bradbury SMJ, Hambley L, Cookson V, Allocca G, Kruithof de Julio M, Coleman RE, Brown JE, Holen I, Ottewell PD. Tulotta C, et al. Clin Cancer Res. 2019 May 1;25(9):2769-2782. doi: 10.1158/1078-0432.CCR-18-2202. Epub 2019 Jan 22. Clin Cancer Res. 2019. PMID: 30670488 Free article.
IL-1B drives opposing responses in primary tumours and bone metastases; harnessing combination therapies to improve outcome in breast cancer.
Tulotta C, Lefley DV, Moore CK, Amariutei AE, Spicer-Hadlington AR, Quayle LA, Hughes RO, Ahmed K, Cookson V, Evans CA, Vadakekolathu J, Heath P, Francis S, Pinteaux E, Pockley AG, Ottewell PD. Tulotta C, et al. NPJ Breast Cancer. 2021 Jul 21;7(1):95. doi: 10.1038/s41523-021-00305-w. NPJ Breast Cancer. 2021. PMID: 34290237 Free PMC article.
Regulation of GTP-binding protein (Gαs) expression in human myometrial cells: a role for tumor necrosis factor in modulating Gαs promoter acetylation by transcriptional complexes.
Webster SJ, Waite SL, Cookson VJ, Warren A, Khan R, Gandhi SV, Europe-Finner GN, Chapman NR. Webster SJ, et al. Among authors: cookson vj. J Biol Chem. 2013 Mar 1;288(9):6704-16. doi: 10.1074/jbc.M112.440602. Epub 2013 Jan 7. J Biol Chem. 2013. PMID: 23297421 Free PMC article. Clinical Trial.
18 results