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Identification of a coordinated CD8 and CD4 T cell response directed against mismatched HLA Class I causing severe acute graft-versus-host disease.
Amir AL, Hagedoorn RS, van Luxemburg-Heijs SA, Marijt EW, Kruisselbrink AB, Frederik Falkenburg JH, Heemskerk MH. Amir AL, et al. Biol Blood Marrow Transplant. 2012 Feb;18(2):210-9. doi: 10.1016/j.bbmt.2011.10.018. Epub 2011 Oct 19. Biol Blood Marrow Transplant. 2012. PMID: 22015995 Free article. Clinical Trial.
Monitoring of indirect allorecognition: wishful thinking or solid data?
Waanders MM, Heidt S, Koekkoek KM, Zoet YM, Doxiadis II, Amir A, Heemskerk MH, Mulder A, Brand A, Roelen DL, Claas FH. Waanders MM, et al. Tissue Antigens. 2008 Jan;71(1):1-15. doi: 10.1111/j.1399-0039.2007.00979.x. Tissue Antigens. 2008. PMID: 18096006 Review.
Allo-HLA reactivity of virus-specific memory T cells is common.
Amir AL, D'Orsogna LJ, Roelen DL, van Loenen MM, Hagedoorn RS, de Boer R, van der Hoorn MA, Kester MG, Doxiadis II, Falkenburg JH, Claas FH, Heemskerk MH. Amir AL, et al. Blood. 2010 Apr 15;115(15):3146-57. doi: 10.1182/blood-2009-07-234906. Epub 2010 Feb 16. Blood. 2010. PMID: 20160165 Free article.
Mixed T cell receptor dimers harbor potentially harmful neoreactivity.
van Loenen MM, de Boer R, Amir AL, Hagedoorn RS, Volbeda GL, Willemze R, van Rood JJ, Falkenburg JH, Heemskerk MH. van Loenen MM, et al. Among authors: amir al. Proc Natl Acad Sci U S A. 2010 Jun 15;107(24):10972-7. doi: 10.1073/pnas.1005802107. Epub 2010 Jun 1. Proc Natl Acad Sci U S A. 2010. PMID: 20534461 Free PMC article.
PRAME-specific Allo-HLA-restricted T cells with potent antitumor reactivity useful for therapeutic T-cell receptor gene transfer.
Amir AL, van der Steen DM, van Loenen MM, Hagedoorn RS, de Boer R, Kester MD, de Ru AH, Lugthart GJ, van Kooten C, Hiemstra PS, Jedema I, Griffioen M, van Veelen PA, Falkenburg JH, Heemskerk MH. Amir AL, et al. Clin Cancer Res. 2011 Sep 1;17(17):5615-25. doi: 10.1158/1078-0432.CCR-11-1066. Epub 2011 Jul 19. Clin Cancer Res. 2011. PMID: 21771875
Paired primary and metastatic lesions of patients with ipilimumab-treated melanoma: high variation in lymphocyte infiltration and HLA-ABC expression whereas tumor mutational load is similar and correlates with clinical outcome.
Gorris MAJ, van der Woude LL, Kroeze LI, Bol K, Verrijp K, Amir AL, Meek J, Textor J, Figdor CG, de Vries IJM. Gorris MAJ, et al. Among authors: amir al. J Immunother Cancer. 2022 May;10(5):e004329. doi: 10.1136/jitc-2021-004329. J Immunother Cancer. 2022. PMID: 35550553 Free PMC article.
23 results