Toker A - Search Results

1

mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR.

Gao D, Inuzuka H, Tan MK, Fukushima H, Locasale JW, Liu P, Wan L, Zhai B, Chin YR, Shaik S, Lyssiotis CA, Gygi SP, Toker A, Cantley LC, Asara JM, Harper JW, Wei W. Gao D, et al. Among authors: toker a. Mol Cell. 2011 Oct 21;44(2):290-303. doi: 10.1016/j.molcel.2011.08.030. Mol Cell. 2011. PMID: 22017875 Free PMC article.

2

Phosphorylation of the platelet p47 phosphoprotein is mediated by the lipid products of phosphoinositide 3-kinase.

Toker A, Bachelot C, Chen CS, Falck JR, Hartwig JH, Cantley LC, Kovacsovics TJ. Toker A, et al. J Biol Chem. 1995 Dec 8;270(49):29525-31. doi: 10.1074/jbc.270.49.29525. J Biol Chem. 1995. PMID: 7493994 Free article.

We have shown previously that these lipids activate calcium-independent protein kinase C (PKC) isoforms in vitro (Toker, A., Meyer, M., Reddy, K. K., Falck, J. R., Aneja, R., Aneja, S., Parra, A., Burns, D. ...These results suggest two modes of stimulating pl …

We have shown previously that these lipids activate calcium-independent protein kinase C (PKC) isoforms in vitro (Toker, A., M …

3

Phosphoinositide 3-kinase binds constitutively to alpha/beta-tubulin and binds to gamma-tubulin in response to insulin.

Kapeller R, Toker A, Cantley LC, Carpenter CL. Kapeller R, et al. Among authors: toker a. J Biol Chem. 1995 Oct 27;270(43):25985-91. doi: 10.1074/jbc.270.43.25985. J Biol Chem. 1995. PMID: 7592789 Free article.

4

Activation of protein kinase C family members by the novel polyphosphoinositides PtdIns-3,4-P2 and PtdIns-3,4,5-P3.

Toker A, Meyer M, Reddy KK, Falck JR, Aneja R, Aneja S, Parra A, Burns DJ, Ballas LM, Cantley LC. Toker A, et al. J Biol Chem. 1994 Dec 23;269(51):32358-67. J Biol Chem. 1994. PMID: 7798235 Free article.

5

D3 phosphoinositides and outside-in integrin signaling by glycoprotein IIb-IIIa mediate platelet actin assembly and filopodial extension induced by phorbol 12-myristate 13-acetate.

Hartwig JH, Kung S, Kovacsovics T, Janmey PA, Cantley LC, Stossel TP, Toker A. Hartwig JH, et al. Among authors: toker a. J Biol Chem. 1996 Dec 20;271(51):32986-93. doi: 10.1074/jbc.271.51.32986. J Biol Chem. 1996. PMID: 8955143 Free article.

6

Determination of the specific substrate sequence motifs of protein kinase C isozymes.

Nishikawa K, Toker A, Johannes FJ, Songyang Z, Cantley LC. Nishikawa K, et al. Among authors: toker a. J Biol Chem. 1997 Jan 10;272(2):952-60. doi: 10.1074/jbc.272.2.952. J Biol Chem. 1997. PMID: 8995387 Free article.

7

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate.

Franke TF, Kaplan DR, Cantley LC, Toker A. Franke TF, et al. Among authors: toker a. Science. 1997 Jan 31;275(5300):665-8. doi: 10.1126/science.275.5300.665. Science. 1997. PMID: 9005852

8

The lipid products of phosphoinositide 3-kinase increase cell motility through protein kinase C.

Derman MP, Toker A, Hartwig JH, Spokes K, Falck JR, Chen CS, Cantley LC, Cantley LG. Derman MP, et al. Among authors: toker a. J Biol Chem. 1997 Mar 7;272(10):6465-70. doi: 10.1074/jbc.272.10.6465. J Biol Chem. 1997. PMID: 9045671 Free article.

9

Identification of a novel pathway important for proliferation and differentiation of primary erythroid progenitors.

Klingmüller U, Wu H, Hsiao JG, Toker A, Duckworth BC, Cantley LC, Lodish HF. Klingmüller U, et al. Among authors: toker a. Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):3016-21. doi: 10.1073/pnas.94.7.3016. Proc Natl Acad Sci U S A. 1997. PMID: 9096338 Free PMC article.

10

Signalling through the lipid products of phosphoinositide-3-OH kinase.

Toker A, Cantley LC. Toker A, et al. Nature. 1997 Jun 12;387(6634):673-6. doi: 10.1038/42648. Nature. 1997. PMID: 9192891 Review.

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