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Myeloid Zfhx3 Deficiency Protects Against Hypercapnia-induced Suppression of Host Defense Against Influenza A Virus.
Casalino-Matsuda SM, Chen F, Gonzalez-Gonzalez FJ, Matsuda H, Nair A, Abdala-Valencia H, Budinger GRS, Dong JT, Beitel GJ, Sporn PHS. Casalino-Matsuda SM, et al. bioRxiv [Preprint]. 2023 Mar 1:2023.02.28.530480. doi: 10.1101/2023.02.28.530480. bioRxiv. 2023. Update in: JCI Insight. 2024 Jan 16;9(4):e170316. doi: 10.1172/jci.insight.170316. PMID: 36909510 Free PMC article. Updated. Preprint.
Alveolitis in severe SARS-CoV-2 pneumonia is driven by self-sustaining circuits between infected alveolar macrophages and T cells.
Grant RA, Morales-Nebreda L, Markov NS, Swaminathan S, Guzman ER, Abbott DA, Donnelly HK, Donayre A, Goldberg IA, Klug ZM, Borkowski N, Lu Z, Kihshen H, Politanska Y, Sichizya L, Kang M, Shilatifard A, Qi C, Argento AC, Kruser JM, Malsin ES, Pickens CO, Smith S, Walter JM, Pawlowski AE, Schneider D, Nannapaneni P, Abdala-Valencia H, Bharat A, Gottardi CJ, Budinger GS, Misharin AV, Singer BD, Wunderink RG; NU SCRIPT Study Investigators. Grant RA, et al. bioRxiv [Preprint]. 2020 Aug 7:2020.08.05.238188. doi: 10.1101/2020.08.05.238188. bioRxiv. 2020. Update in: Nature. 2021 Feb;590(7847):635-641. doi: 10.1038/s41586-020-03148-w. PMID: 34013276 Free PMC article. Updated. Preprint.
A distinctive evolution of alveolar T cell responses is associated with clinical outcomes in unvaccinated patients with SARS-CoV-2 pneumonia.
Markov NS, Ren Z, Senkow KJ, Grant RA, Gao CA, Malsin ES, Sichizya L, Kihshen H, Helmin KA, Jovisic M, Arnold JM, Pérez-Leonor XG, Abdala-Valencia H, Swaminathan S, Nwaezeapu J, Kang M, Rasmussen L, Ozer EA, Lorenzo-Redondo R, Hultquist JF, Simons LM, Rios-Guzman E, Misharin AV, Wunderink RG, Budinger GRS, Singer BD, Morales-Nebreda L; NU SCRIPT Study Investigators. Markov NS, et al. Among authors: abdala valencia h. bioRxiv [Preprint]. 2023 Dec 14:2023.12.13.571479. doi: 10.1101/2023.12.13.571479. bioRxiv. 2023. Update in: Nat Immunol. 2024 Sep;25(9):1607-1622. doi: 10.1038/s41590-024-01914-w. PMID: 38168346 Free PMC article. Updated. Preprint.
Aging is associated with a systemic length-associated transcriptome imbalance.
Stoeger T, Grant RA, McQuattie-Pimentel AC, Anekalla KR, Liu SS, Tejedor-Navarro H, Singer BD, Abdala-Valencia H, Schwake M, Tetreault MP, Perlman H, Balch WE, Chandel NS, Ridge KM, Sznajder JI, Morimoto RI, Misharin AV, Budinger GRS, Nunes Amaral LA. Stoeger T, et al. Nat Aging. 2022 Dec;2(12):1191-1206. doi: 10.1038/s43587-022-00317-6. Epub 2022 Dec 9. Nat Aging. 2022. PMID: 37118543 Free PMC article.
Galphai2-mediated signaling events in the endothelium are involved in controlling leukocyte extravasation.
Pero RS, Borchers MT, Spicher K, Ochkur SI, Sikora L, Rao SP, Abdala-Valencia H, O'Neill KR, Shen H, McGarry MP, Lee NA, Cook-Mills JM, Sriramarao P, Simon MI, Birnbaumer L, Lee JJ. Pero RS, et al. Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4371-6. doi: 10.1073/pnas.0700185104. Epub 2007 Mar 7. Proc Natl Acad Sci U S A. 2007. PMID: 17360531 Free PMC article.
88 results