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Page 1
Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast.
Treusch S, Hamamichi S, Goodman JL, Matlack KE, Chung CY, Baru V, Shulman JM, Parrado A, Bevis BJ, Valastyan JS, Han H, Lindhagen-Persson M, Reiman EM, Evans DA, Bennett DA, Olofsson A, DeJager PL, Tanzi RE, Caldwell KA, Caldwell GA, Lindquist S. Treusch S, et al. Among authors: parrado a. Science. 2011 Dec 2;334(6060):1241-5. doi: 10.1126/science.1213210. Epub 2011 Oct 27. Science. 2011. PMID: 22033521 Free PMC article.
TREM2 and neurodegenerative disease.
Bertram L, Parrado AR, Tanzi RE. Bertram L, et al. N Engl J Med. 2013 Oct 17;369(16):1565. doi: 10.1056/NEJMc1306509. N Engl J Med. 2013. PMID: 24131185 No abstract available.
Alzheimer's disease risk gene CD33 inhibits microglial uptake of amyloid beta.
Griciuc A, Serrano-Pozo A, Parrado AR, Lesinski AN, Asselin CN, Mullin K, Hooli B, Choi SH, Hyman BT, Tanzi RE. Griciuc A, et al. Among authors: parrado ar. Neuron. 2013 May 22;78(4):631-43. doi: 10.1016/j.neuron.2013.04.014. Epub 2013 Apr 25. Neuron. 2013. PMID: 23623698 Free PMC article.
Relevance of the COPI complex for Alzheimer's disease progression in vivo.
Bettayeb K, Hooli BV, Parrado AR, Randolph L, Varotsis D, Aryal S, Gresack J, Tanzi RE, Greengard P, Flajolet M. Bettayeb K, et al. Proc Natl Acad Sci U S A. 2016 May 10;113(19):5418-23. doi: 10.1073/pnas.1604176113. Epub 2016 Apr 25. Proc Natl Acad Sci U S A. 2016. PMID: 27114526 Free PMC article.
Role of common and rare APP DNA sequence variants in Alzheimer disease.
Hooli BV, Mohapatra G, Mattheisen M, Parrado AR, Roehr JT, Shen Y, Gusella JF, Moir R, Saunders AJ, Lange C, Tanzi RE, Bertram L. Hooli BV, et al. Among authors: parrado ar. Neurology. 2012 Apr 17;78(16):1250-7. doi: 10.1212/WNL.0b013e3182515972. Epub 2012 Apr 4. Neurology. 2012. PMID: 22491860 Free PMC article.
Cysteine 27 variant of the delta-opioid receptor affects amyloid precursor protein processing through altered endocytic trafficking.
Sarajärvi T, Tuusa JT, Haapasalo A, Lackman JJ, Sormunen R, Helisalmi S, Roehr JT, Parrado AR, Mäkinen P, Bertram L, Soininen H, Tanzi RE, Petäjä-Repo UE, Hiltunen M. Sarajärvi T, et al. Among authors: parrado ar. Mol Cell Biol. 2011 Jun;31(11):2326-40. doi: 10.1128/MCB.05015-11. Epub 2011 Apr 4. Mol Cell Biol. 2011. PMID: 21464208 Free PMC article.
The rare TREM2 R47H variant exerts only a modest effect on Alzheimer disease risk.
Hooli BV, Parrado AR, Mullin K, Yip WK, Liu T, Roehr JT, Qiao D, Jessen F, Peters O, Becker T, Ramirez A, Lange C, Bertram L, Tanzi RE. Hooli BV, et al. Among authors: parrado ar. Neurology. 2014 Oct 7;83(15):1353-8. doi: 10.1212/WNL.0000000000000855. Epub 2014 Sep 3. Neurology. 2014. PMID: 25186855 Free PMC article.
Elucidation of the BACE1 regulating factor GGA3 in Alzheimer's disease.
Natunen T, Parrado AR, Helisalmi S, Pursiheimo JP, Sarajärvi T, Mäkinen P, Kurkinen KM, Mullin K, Alafuzoff I, Haapasalo A, Bertram L, Soininen H, Tanzi RE, Hiltunen M. Natunen T, et al. Among authors: parrado ar. J Alzheimers Dis. 2013;37(1):217-32. doi: 10.3233/JAD-130104. J Alzheimers Dis. 2013. PMID: 23970038
Multiple loci influencing hippocampal degeneration identified by genome scan.
Melville SA, Buros J, Parrado AR, Vardarajan B, Logue MW, Shen L, Risacher SL, Kim S, Jun G, DeCarli C, Lunetta KL, Baldwin CT, Saykin AJ, Farrer LA; Alzheimer's Disease Neuroimaging Initiative. Melville SA, et al. Among authors: parrado ar. Ann Neurol. 2012 Jul;72(1):65-75. doi: 10.1002/ana.23644. Epub 2012 Jun 28. Ann Neurol. 2012. PMID: 22745009 Free PMC article.
78 results