Cheng X - Search Results

1

5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging.

Szulwach KE, Li X, Li Y, Song CX, Wu H, Dai Q, Irier H, Upadhyay AK, Gearing M, Levey AI, Vasanthakumar A, Godley LA, Chang Q, Cheng X, He C, Jin P. Szulwach KE, et al. Among authors: cheng x. Nat Neurosci. 2011 Oct 30;14(12):1607-16. doi: 10.1038/nn.2959. Nat Neurosci. 2011. PMID: 22037496 Free PMC article.

2

Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation.

Jia D, Jurkowska RZ, Zhang X, Jeltsch A, Cheng X. Jia D, et al. Among authors: cheng x. Nature. 2007 Sep 13;449(7159):248-51. doi: 10.1038/nature06146. Epub 2007 Aug 22. Nature. 2007. PMID: 17713477 Free PMC article.

3

The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix.

Hashimoto H, Horton JR, Zhang X, Bostick M, Jacobsen SE, Cheng X. Hashimoto H, et al. Among authors: cheng x. Nature. 2008 Oct 9;455(7214):826-9. doi: 10.1038/nature07280. Epub 2008 Sep 3. Nature. 2008. PMID: 18772888 Free PMC article.

4

Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294.

Chang Y, Zhang X, Horton JR, Upadhyay AK, Spannhoff A, Liu J, Snyder JP, Bedford MT, Cheng X. Chang Y, et al. Among authors: cheng x. Nat Struct Mol Biol. 2009 Mar;16(3):312-7. doi: 10.1038/nsmb.1560. Epub 2009 Feb 15. Nat Struct Mol Biol. 2009. PMID: 19219047 Free PMC article.

5

Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.

Horton JR, Upadhyay AK, Qi HH, Zhang X, Shi Y, Cheng X. Horton JR, et al. Among authors: cheng x. Nat Struct Mol Biol. 2010 Jan;17(1):38-43. doi: 10.1038/nsmb.1753. Epub 2009 Dec 20. Nat Struct Mol Biol. 2010. PMID: 20023638 Free PMC article.

6

hNaa10p contributes to tumorigenesis by facilitating DNMT1-mediated tumor suppressor gene silencing.

Lee CF, Ou DS, Lee SB, Chang LH, Lin RK, Li YS, Upadhyay AK, Cheng X, Wang YC, Hsu HS, Hsiao M, Wu CW, Juan LJ. Lee CF, et al. Among authors: cheng x. J Clin Invest. 2010 Aug;120(8):2920-30. doi: 10.1172/JCI42275. Epub 2010 Jul 1. J Clin Invest. 2010. PMID: 20592467 Free PMC article.

7

Dynamics of histone lysine methylation: structures of methyl writers and erasers.

Upadhyay AK, Cheng X. Upadhyay AK, et al. Among authors: cheng x. Prog Drug Res. 2011;67:107-24. doi: 10.1007/978-3-7643-8989-5_6. Prog Drug Res. 2011. PMID: 21141727 Free PMC article. Review.

8

A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability.

Estève PO, Chang Y, Samaranayake M, Upadhyay AK, Horton JR, Feehery GR, Cheng X, Pradhan S. Estève PO, et al. Among authors: cheng x. Nat Struct Mol Biol. 2011 Jan;18(1):42-8. doi: 10.1038/nsmb.1939. Epub 2010 Dec 12. Nat Struct Mol Biol. 2011. PMID: 21151116 Free PMC article.

9

Structural basis for human PHF2 Jumonji domain interaction with metal ions.

Horton JR, Upadhyay AK, Hashimoto H, Zhang X, Cheng X. Horton JR, et al. Among authors: cheng x. J Mol Biol. 2011 Feb 11;406(1):1-8. doi: 10.1016/j.jmb.2010.12.013. Epub 2010 Dec 15. J Mol Biol. 2011. PMID: 21167174 Free PMC article.

10

Coordinated methyl-lysine erasure: structural and functional linkage of a Jumonji demethylase domain and a reader domain.

Upadhyay AK, Horton JR, Zhang X, Cheng X. Upadhyay AK, et al. Among authors: cheng x. Curr Opin Struct Biol. 2011 Dec;21(6):750-60. doi: 10.1016/j.sbi.2011.08.003. Epub 2011 Aug 25. Curr Opin Struct Biol. 2011. PMID: 21872465 Free PMC article.

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