Cini E - Search Results

1

Downregulation of hypoxia-related responses by novel antitumor histone deacetylase inhibitors in MDAMB231 breast cancer cells.

Naldini A, Filippi I, Cini E, Rodriquez M, Carraro F, Taddei M. Naldini A, et al. Among authors: cini e. Anticancer Agents Med Chem. 2012 May;12(4):407-13. doi: 10.2174/187152012800228706. Anticancer Agents Med Chem. 2012. PMID: 22043993

2

Total synthesis, NMR solution structure, and binding model of the potent histone deacetylase inhibitor FR235222.

Rodriquez M, Terracciano S, Cini E, Settembrini G, Bruno I, Bifulco G, Taddei M, Gomez-Paloma L. Rodriquez M, et al. Among authors: cini e. Angew Chem Int Ed Engl. 2006 Jan 9;45(3):423-7. doi: 10.1002/anie.200501995. Angew Chem Int Ed Engl. 2006. PMID: 16311994 No abstract available.

3

Synthesis of 2-amino-8-oxodecanoic acids (Aodas) present in natural hystone deacetylase inhibitors.

Rodriquez M, Bruno I, Cini E, Marchetti M, Taddei M, Gomez-Paloma L. Rodriquez M, et al. Among authors: cini e. J Org Chem. 2006 Jan 6;71(1):103-7. doi: 10.1021/jo0518250. J Org Chem. 2006. PMID: 16388624

4

Design and synthesis of cyclopeptide analogues of the potent histone deacetylase inhibitor FR235222.

Gomez-Paloma L, Bruno I, Cini E, Khochbin S, Rodriquez M, Taddei M, Terracciano S, Sadoul K. Gomez-Paloma L, et al. Among authors: cini e. ChemMedChem. 2007 Oct;2(10):1511-9. doi: 10.1002/cmdc.200700095. ChemMedChem. 2007. PMID: 17694590

5

Oxime amides as a novel zinc binding group in histone deacetylase inhibitors: synthesis, biological activity, and computational evaluation.

Botta CB, Cabri W, Cini E, De Cesare L, Fattorusso C, Giannini G, Persico M, Petrella A, Rondinelli F, Rodriquez M, Russo A, Taddei M. Botta CB, et al. Among authors: cini e. J Med Chem. 2011 Apr 14;54(7):2165-82. doi: 10.1021/jm101373a. Epub 2011 Mar 18. J Med Chem. 2011. PMID: 21417297

6

Lactam based 7-amino suberoylamide hydroxamic acids as potent HDAC inhibitors.

Taddei M, Cini E, Giannotti L, Giannini G, Battistuzzi G, Vignola D, Vesci L, Cabri W. Taddei M, et al. Among authors: cini e. Bioorg Med Chem Lett. 2014 Jan 1;24(1):61-4. doi: 10.1016/j.bmcl.2013.11.072. Epub 2013 Dec 4. Bioorg Med Chem Lett. 2014. PMID: 24345446

7

Benzodiazepine Scaffold as Drug-like Molecular Simplification of FR235222: A Chemical Tool for Exploring HDAC Inhibition.

Randino R, Moronese I, Cini E, Bizzarro V, Persico M, Grimaldi M, Scrima M, D'Ursi AM, Novellino E, Sobarzo-Sanchez E, Rastrelli L, Fattorusso C, Petrella A, Rodriquez M, Taddei M. Randino R, et al. Among authors: cini e. Curr Top Med Chem. 2017;17(4):441-459. doi: 10.2174/1568026616666160824105645. Curr Top Med Chem. 2017. PMID: 27558677

8

Investigating the Neuroprotective Effects of Turmeric Extract: Structural Interactions of β-Amyloid Peptide with Single Curcuminoids.

Randino R, Grimaldi M, Persico M, De Santis A, Cini E, Cabri W, Riva A, D'Errico G, Fattorusso C, D'Ursi AM, Rodriquez M. Randino R, et al. Among authors: cini e. Sci Rep. 2016 Dec 22;6:38846. doi: 10.1038/srep38846. Sci Rep. 2016. PMID: 28004737 Free PMC article.

9

Antibody drug conjugates (ADCs) charged with HDAC inhibitor for targeted epigenetic modulation.

Cini E, Faltoni V, Petricci E, Taddei M, Salvini L, Giannini G, Vesci L, Milazzo FM, Anastasi AM, Battistuzzi G, De Santis R. Cini E, et al. Chem Sci. 2018 Jul 3;9(31):6490-6496. doi: 10.1039/c7sc05266a. eCollection 2018 Aug 21. Chem Sci. 2018. PMID: 30288233 Free PMC article.

10

ErbB2 Targeted Epigenetic Modulation: Anti-tumor Efficacy of the ADC Trastuzumab-HDACi ST8176AA1.

Milazzo FM, Vesci L, Anastasi AM, Chiapparino C, Rosi A, Giannini G, Taddei M, Cini E, Faltoni V, Petricci E, Battistuzzi G, Salvini L, Carollo V, De Santis R. Milazzo FM, et al. Among authors: cini e. Front Oncol. 2020 Jan 23;9:1534. doi: 10.3389/fonc.2019.01534. eCollection 2019. Front Oncol. 2020. PMID: 32039017 Free PMC article.

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