Hughes LA - Search Results

1

The CpG island methylator phenotype in colorectal cancer: progress and problems.

Hughes LA, Khalid-de Bakker CA, Smits KM, van den Brandt PA, Jonkers D, Ahuja N, Herman JG, Weijenberg MP, van Engeland M. Hughes LA, et al. Biochim Biophys Acta. 2012 Jan;1825(1):77-85. doi: 10.1016/j.bbcan.2011.10.005. Epub 2011 Oct 28. Biochim Biophys Acta. 2012. PMID: 22056543 Review.

2

A novel classification of colorectal tumors based on microsatellite instability, the CpG island methylator phenotype and chromosomal instability: implications for prognosis.

Simons CC, Hughes LA, Smits KM, Khalid-de Bakker CA, de Bruïne AP, Carvalho B, Meijer GA, Schouten LJ, van den Brandt PA, Weijenberg MP, van Engeland M. Simons CC, et al. Among authors: hughes la. Ann Oncol. 2013 Aug;24(8):2048-56. doi: 10.1093/annonc/mdt076. Epub 2013 Mar 26. Ann Oncol. 2013. PMID: 23532114 Free article.

3

Early life exposure to famine and colorectal cancer risk: a role for epigenetic mechanisms.

Hughes LA, van den Brandt PA, de Bruïne AP, Wouters KA, Hulsmans S, Spiertz A, Goldbohm RA, de Goeij AF, Herman JG, Weijenberg MP, van Engeland M. Hughes LA, et al. PLoS One. 2009 Nov 23;4(11):e7951. doi: 10.1371/journal.pone.0007951. PLoS One. 2009. PMID: 19956740 Free PMC article.

4

Body size, physical activity and risk of colorectal cancer with or without the CpG island methylator phenotype (CIMP).

Hughes LA, Simons CC, van den Brandt PA, Goldbohm RA, de Goeij AF, de Bruïne AP, van Engeland M, Weijenberg MP. Hughes LA, et al. PLoS One. 2011 Apr 5;6(4):e18571. doi: 10.1371/journal.pone.0018571. PLoS One. 2011. PMID: 21483668 Free PMC article.

5

The CpG island methylator phenotype: what's in a name?

Hughes LA, Melotte V, de Schrijver J, de Maat M, Smit VT, Bovée JV, French PJ, van den Brandt PA, Schouten LJ, de Meyer T, van Criekinge W, Ahuja N, Herman JG, Weijenberg MP, van Engeland M. Hughes LA, et al. Cancer Res. 2013 Oct 1;73(19):5858-68. doi: 10.1158/0008-5472.CAN-12-4306. Epub 2013 Jun 25. Cancer Res. 2013. PMID: 23801749

6

Pharmacoepigenomics in colorectal cancer: a step forward in predicting prognosis and treatment response.

Smits KM, Cleven AH, Weijenberg MP, Hughes LA, Herman JG, de Bruïne AP, van Engeland M. Smits KM, et al. Among authors: hughes la. Pharmacogenomics. 2008 Dec;9(12):1903-16. doi: 10.2217/14622416.9.12.1903. Pharmacogenomics. 2008. PMID: 19072647 Review.

7

Dietary flavonol, flavone and catechin intake and risk of colorectal cancer in the Netherlands Cohort Study.

Simons CC, Hughes LA, Arts IC, Goldbohm RA, van den Brandt PA, Weijenberg MP. Simons CC, et al. Among authors: hughes la. Int J Cancer. 2009 Dec 15;125(12):2945-52. doi: 10.1002/ijc.24645. Int J Cancer. 2009. PMID: 19530252

8

Childhood and adolescent energy restriction and subsequent colorectal cancer risk: results from the Netherlands Cohort Study.

Hughes LA, van den Brandt PA, Goldbohm RA, de Goeij AF, de Bruïne AP, van Engeland M, Weijenberg MP. Hughes LA, et al. Int J Epidemiol. 2010 Oct;39(5):1333-44. doi: 10.1093/ije/dyq062. Epub 2010 Apr 28. Int J Epidemiol. 2010. PMID: 20427463

9

Body size and colorectal cancer risk after 16.3 years of follow-up: an analysis from the Netherlands Cohort Study.

Hughes LA, Simons CC, van den Brandt PA, Goldbohm RA, van Engeland M, Weijenberg MP. Hughes LA, et al. Am J Epidemiol. 2011 Nov 15;174(10):1127-39. doi: 10.1093/aje/kwr247. Epub 2011 Oct 7. Am J Epidemiol. 2011. PMID: 21984660

10

Body size and risk for colorectal cancers showing BRAF mutations or microsatellite instability: a pooled analysis.

Hughes LA, Williamson EJ, van Engeland M, Jenkins MA, Giles GG, Hopper JL, Southey MC, Young JP, Buchanan DD, Walsh MD, van den Brandt PA, Alexandra Goldbohm R, Weijenberg MP, English DR. Hughes LA, et al. Int J Epidemiol. 2012 Aug;41(4):1060-72. doi: 10.1093/ije/dys055. Epub 2012 Apr 24. Int J Epidemiol. 2012. PMID: 22531127

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