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937 results

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An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent pathway.
Guo D, Reinitz F, Youssef M, Hong C, Nathanson D, Akhavan D, Kuga D, Amzajerdi AN, Soto H, Zhu S, Babic I, Tanaka K, Dang J, Iwanami A, Gini B, Dejesus J, Lisiero DD, Huang TT, Prins RM, Wen PY, Robins HI, Prados MD, Deangelis LM, Mellinghoff IK, Mehta MP, James CD, Chakravarti A, Cloughesy TF, Tontonoz P, Mischel PS. Guo D, et al. Among authors: chakravarti a. Cancer Discov. 2011 Oct;1(5):442-56. doi: 10.1158/2159-8290.CD-11-0102. Epub 2011 Sep 15. Cancer Discov. 2011. PMID: 22059152 Free PMC article.
Targeting SREBP-1-driven lipid metabolism to treat cancer.
Guo D, Bell EH, Mischel P, Chakravarti A. Guo D, et al. Among authors: chakravarti a. Curr Pharm Des. 2014;20(15):2619-26. doi: 10.2174/13816128113199990486. Curr Pharm Des. 2014. PMID: 23859617 Free PMC article. Review.
RTOG 0211: a phase 1/2 study of radiation therapy with concurrent gefitinib for newly diagnosed glioblastoma patients.
Chakravarti A, Wang M, Robins HI, Lautenschlaeger T, Curran WJ, Brachman DG, Schultz CJ, Choucair A, Dolled-Filhart M, Christiansen J, Gustavson M, Molinaro A, Mischel P, Dicker AP, Bredel M, Mehta M. Chakravarti A, et al. Int J Radiat Oncol Biol Phys. 2013 Apr 1;85(5):1206-11. doi: 10.1016/j.ijrobp.2012.10.008. Epub 2012 Nov 22. Int J Radiat Oncol Biol Phys. 2013. PMID: 23182702 Free PMC article. Clinical Trial.
Current therapeutic paradigms in glioblastoma.
Quick A, Patel D, Hadziahmetovic M, Chakravarti A, Mehta M. Quick A, et al. Among authors: chakravarti a. Rev Recent Clin Trials. 2010 Jan;5(1):14-27. doi: 10.2174/157488710790820544. Rev Recent Clin Trials. 2010. PMID: 20205684 Review.
Inhibition of SOAT1 Suppresses Glioblastoma Growth via Blocking SREBP-1-Mediated Lipogenesis.
Geng F, Cheng X, Wu X, Yoo JY, Cheng C, Guo JY, Mo X, Ru P, Hurwitz B, Kim SH, Otero J, Puduvalli V, Lefai E, Ma J, Nakano I, Horbinski C, Kaur B, Chakravarti A, Guo D. Geng F, et al. Among authors: chakravarti a. Clin Cancer Res. 2016 Nov 1;22(21):5337-5348. doi: 10.1158/1078-0432.CCR-15-2973. Epub 2016 Jun 8. Clin Cancer Res. 2016. PMID: 27281560 Free PMC article.
Development of a real-time RT-PCR assay for detecting EGFRvIII in glioblastoma samples.
Yoshimoto K, Dang J, Zhu S, Nathanson D, Huang T, Dumont R, Seligson DB, Yong WH, Xiong Z, Rao N, Winther H, Chakravarti A, Bigner DD, Mellinghoff IK, Horvath S, Cavenee WK, Cloughesy TF, Mischel PS. Yoshimoto K, et al. Among authors: chakravarti a. Clin Cancer Res. 2008 Jan 15;14(2):488-93. doi: 10.1158/1078-0432.CCR-07-1966. Clin Cancer Res. 2008. PMID: 18223223
937 results