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Page 1
3-Formylchromone interacts with cysteine 38 in p65 protein and with cysteine 179 in IκBα kinase, leading to down-regulation of nuclear factor-κB (NF-κB)-regulated gene products and sensitization of tumor cells.
Yadav VR, Prasad S, Gupta SC, Sung B, Phatak SS, Zhang S, Aggarwal BB. Yadav VR, et al. J Biol Chem. 2012 Jan 2;287(1):245-256. doi: 10.1074/jbc.M111.274613. Epub 2011 Nov 7. J Biol Chem. 2012. Retraction in: J Biol Chem. 2016 Aug 5;291(32):16926. doi: 10.1074/jbc.A111.274613 PMID: 22065587 Free PMC article. Retracted.
NF-κB addiction and its role in cancer: 'one size does not fit all'.
Chaturvedi MM, Sung B, Yadav VR, Kannappan R, Aggarwal BB. Chaturvedi MM, et al. Among authors: yadav vr. Oncogene. 2011 Apr 7;30(14):1615-30. doi: 10.1038/onc.2010.566. Epub 2010 Dec 20. Oncogene. 2011. PMID: 21170083 Free PMC article. Review.
Celastrol, a triterpene, enhances TRAIL-induced apoptosis through the down-regulation of cell survival proteins and up-regulation of death receptors.
Sung B, Park B, Yadav VR, Aggarwal BB. Sung B, et al. Among authors: yadav vr. J Biol Chem. 2010 Apr 9;285(15):11498-507. doi: 10.1074/jbc.M109.090209. Epub 2010 Feb 12. J Biol Chem. 2010. Retraction in: J Biol Chem. 2016 Aug 5;291(32):16920. doi: 10.1074/jbc.A109.090209 PMID: 20154087 Free PMC article. Retracted.
Crotepoxide chemosensitizes tumor cells through inhibition of expression of proliferation, invasion, and angiogenic proteins linked to proinflammatory pathway.
Prasad S, Yadav VR, Sundaram C, Reuter S, Hema PS, Nair MS, Chaturvedi MM, Aggarwal BB. Prasad S, et al. Among authors: yadav vr. J Biol Chem. 2010 Aug 27;285(35):26987-27000. doi: 10.1074/jbc.M110.121061. Epub 2010 Jun 23. J Biol Chem. 2010. Retraction in: J Biol Chem. 2016 Aug 5;291(32):16921. doi: 10.1074/jbc.A110.121061 PMID: 20576605 Free PMC article. Retracted.
γ-Tocotrienol but not γ-tocopherol blocks STAT3 cell signaling pathway through induction of protein-tyrosine phosphatase SHP-1 and sensitizes tumor cells to chemotherapeutic agents.
Kannappan R, Yadav VR, Aggarwal BB. Kannappan R, et al. Among authors: yadav vr. J Biol Chem. 2010 Oct 22;285(43):33520-33529. doi: 10.1074/jbc.M110.158378. Epub 2010 Aug 18. J Biol Chem. 2010. Retraction in: J Biol Chem. 2016 Aug 5;291(32):16922. doi: 10.1074/jbc.A110.158378 PMID: 20720018 Free PMC article. Retracted.
Modification of cysteine 179 of IkappaBalpha kinase by nimbolide leads to down-regulation of NF-kappaB-regulated cell survival and proliferative proteins and sensitization of tumor cells to chemotherapeutic agents.
Gupta SC, Prasad S, Reuter S, Kannappan R, Yadav VR, Ravindran J, Hema PS, Chaturvedi MM, Nair M, Aggarwal BB. Gupta SC, et al. Among authors: yadav vr. J Biol Chem. 2010 Nov 12;285(46):35406-17. doi: 10.1074/jbc.M110.161984. Epub 2010 Sep 9. J Biol Chem. 2010. PMID: 20829362 Free PMC article.
A novel pentamethoxyflavone down-regulates tumor cell survival and proliferative and angiogenic gene products through inhibition of IκB kinase activation and sensitizes tumor cells to apoptosis by cytokines and chemotherapeutic agents.
Phromnoi K, Reuter S, Sung B, Prasad S, Kannappan R, Yadav VR, Chanmahasathien W, Limtrakul P, Aggarwal BB. Phromnoi K, et al. Among authors: yadav vr. Mol Pharmacol. 2011 Feb;79(2):279-89. doi: 10.1124/mol.110.067512. Epub 2010 Oct 7. Mol Pharmacol. 2011. Retraction in: Mol Pharmacol. 2016 Jul;90(1):64. doi: 10.1124/mol.115.067512retraction PMID: 20930110 Free PMC article. Retracted.
Thiocolchicoside exhibits anticancer effects through downregulation of NF-κB pathway and its regulated gene products linked to inflammation and cancer.
Reuter S, Prasad S, Phromnoi K, Ravindran J, Sung B, Yadav VR, Kannappan R, Chaturvedi MM, Aggarwal BB. Reuter S, et al. Among authors: yadav vr. Cancer Prev Res (Phila). 2010 Nov;3(11):1462-72. doi: 10.1158/1940-6207.CAPR-10-0037. Epub 2010 Oct 26. Cancer Prev Res (Phila). 2010. PMID: 20978115 Free PMC article.
Ursolic acid, a pentacyclin triterpene, potentiates TRAIL-induced apoptosis through p53-independent up-regulation of death receptors: evidence for the role of reactive oxygen species and JNK.
Prasad S, Yadav VR, Kannappan R, Aggarwal BB. Prasad S, et al. Among authors: yadav vr. J Biol Chem. 2011 Feb 18;286(7):5546-57. doi: 10.1074/jbc.M110.183699. Epub 2010 Dec 14. J Biol Chem. 2011. Retraction in: J Biol Chem. 2016 Aug 5;291(32):16924. doi: 10.1074/jbc.A110.183699 PMID: 21156789 Free PMC article. Retracted.
69 results