Lim CU - Search Results

1

Effects of conditional depletion of topoisomerase II on cell cycle progression in mammalian cells.

Gonzalez RE, Lim CU, Cole K, Bianchini CH, Schools GP, Davis BE, Wada I, Roninson IB, Broude EV. Gonzalez RE, et al. Among authors: lim cu. Cell Cycle. 2011 Oct 15;10(20):3505-14. doi: 10.4161/cc.10.20.17778. Cell Cycle. 2011. PMID: 22067657 Free PMC article.

2

Identification of intergenic trans-regulatory RNAs containing a disease-linked SNP sequence and targeting cell cycle progression/differentiation pathways in multiple common human disorders.

Glinskii AB, Ma J, Ma S, Grant D, Lim CU, Sell S, Glinsky GV. Glinskii AB, et al. Among authors: lim cu. Cell Cycle. 2009 Dec;8(23):3925-42. doi: 10.4161/cc.8.23.10113. Epub 2009 Dec 17. Cell Cycle. 2009. PMID: 19923886

3

Tumor-specific silencing of COPZ2 gene encoding coatomer protein complex subunit ζ 2 renders tumor cells dependent on its paralogous gene COPZ1.

Shtutman M, Baig M, Levina E, Hurteau G, Lim CU, Broude E, Nikiforov M, Harkins TT, Carmack CS, Ding Y, Wieland F, Buttyan R, Roninson IB. Shtutman M, et al. Among authors: lim cu. Proc Natl Acad Sci U S A. 2011 Jul 26;108(30):12449-54. doi: 10.1073/pnas.1103842108. Epub 2011 Jul 11. Proc Natl Acad Sci U S A. 2011. PMID: 21746916 Free PMC article.

4

Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities.

Porter DC, Farmaki E, Altilia S, Schools GP, West DK, Chen M, Chang BD, Puzyrev AT, Lim CU, Rokow-Kittell R, Friedhoff LT, Papavassiliou AG, Kalurupalle S, Hurteau G, Shi J, Baran PS, Gyorffy B, Wentland MP, Broude EV, Kiaris H, Roninson IB. Porter DC, et al. Among authors: lim cu. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13799-804. doi: 10.1073/pnas.1206906109. Epub 2012 Aug 6. Proc Natl Acad Sci U S A. 2012. PMID: 22869755 Free PMC article.

5

Identification of novel genes that regulate androgen receptor signaling and growth of androgen-deprived prostate cancer cells.

Levina E, Ji H, Chen M, Baig M, Oliver D, Ohouo P, Lim CU, Schools G, Carmack S, Ding Y, Broude EV, Roninson IB, Buttyan R, Shtutman M. Levina E, et al. Among authors: lim cu. Oncotarget. 2015 May 30;6(15):13088-104. doi: 10.18632/oncotarget.3743. Oncotarget. 2015. PMID: 26036626 Free PMC article.

6

Inhibition of CDK8 mediator kinase suppresses estrogen dependent transcription and the growth of estrogen receptor positive breast cancer.

McDermott MS, Chumanevich AA, Lim CU, Liang J, Chen M, Altilia S, Oliver D, Rae JM, Shtutman M, Kiaris H, Győrffy B, Roninson IB, Broude EV. McDermott MS, et al. Among authors: lim cu. Oncotarget. 2017 Feb 21;8(8):12558-12575. doi: 10.18632/oncotarget.14894. Oncotarget. 2017. PMID: 28147342 Free PMC article.

7

CDK8/19 Mediator kinases potentiate induction of transcription by NFκB.

Chen M, Liang J, Ji H, Yang Z, Altilia S, Hu B, Schronce A, McDermott MSJ, Schools GP, Lim CU, Oliver D, Shtutman MS, Lu T, Stark GR, Porter DC, Broude EV, Roninson IB. Chen M, et al. Among authors: lim cu. Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10208-10213. doi: 10.1073/pnas.1710467114. Epub 2017 Aug 30. Proc Natl Acad Sci U S A. 2017. PMID: 28855340 Free PMC article.

8

CDK8 Selectively Promotes the Growth of Colon Cancer Metastases in the Liver by Regulating Gene Expression of TIMP3 and Matrix Metalloproteinases.

Liang J, Chen M, Hughes D, Chumanevich AA, Altilia S, Kaza V, Lim CU, Kiaris H, Mythreye K, Pena MM, Broude EV, Roninson IB. Liang J, et al. Among authors: lim cu. Cancer Res. 2018 Dec 1;78(23):6594-6606. doi: 10.1158/0008-5472.CAN-18-1583. Epub 2018 Sep 5. Cancer Res. 2018. PMID: 30185549 Free PMC article.

9

The Inhibition of CDK8/19 Mediator Kinases Prevents the Development of Resistance to EGFR-Targeting Drugs.

Sharko AC, Lim CU, McDermott MSJ, Hennes C, Philavong KP, Aiken T, Tatarskiy VV, Roninson IB, Broude EV. Sharko AC, et al. Among authors: lim cu. Cells. 2021 Jan 12;10(1):144. doi: 10.3390/cells10010144. Cells. 2021. PMID: 33445730 Free PMC article.

10

Mediator kinase inhibition reverses castration resistance of advanced prostate cancer.

Li J, Hilimire TA, Liu Y, Wang L, Liang J, Gyorffy B, Sikirzhytski V, Ji H, Zhang L, Cheng C, Ding X, Kerr KR, Dowling CE, Chumanevich AA, Mack ZT, Schools GP, Lim CU, Ellis L, Zi X, Porter DC, Broude EV, McInnes C, Wilding G, Lilly MB, Roninson IB, Chen M. Li J, et al. Among authors: lim cu. J Clin Invest. 2024 Mar 28;134(10):e176709. doi: 10.1172/JCI176709. J Clin Invest. 2024. PMID: 38546787 Free PMC article.

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