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Page 1
Genetic variations in the CYP17A1 and NT5C2 genes are associated with a reduction in visceral and subcutaneous fat areas in Japanese women.
Hotta K, Kitamoto A, Kitamoto T, Mizusawa S, Teranishi H, Matsuo T, Nakata Y, Hyogo H, Ochi H, Nakamura T, Kamohara S, Miyatake N, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Yoneda M, Nakajima A, Funahashi T, Miyazaki S, Tokunaga K, Masuzaki H, Ueno T, Chayama K, Hamaguchi K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Sakata T, Tanaka K, Matsuzawa Y, Nakao K, Sekine A. Hotta K, et al. J Hum Genet. 2012 Jan;57(1):46-51. doi: 10.1038/jhg.2011.127. Epub 2011 Nov 10. J Hum Genet. 2012. PMID: 22071413 Free article.
Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity.
Tanabe A, Yanagiya T, Iida A, Saito S, Sekine A, Takahashi A, Nakamura T, Tsunoda T, Kamohara S, Nakata Y, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Funahashi T, Miyazaki S, Tokunaga K, Hamaguchi K, Shimada T, Tanaka K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Sakata T, Matsuzawa Y, Kamatani N, Nakamura Y, Hotta K. Tanabe A, et al. Among authors: hotta k. J Clin Endocrinol Metab. 2007 Mar;92(3):1145-54. doi: 10.1210/jc.2006-1808. Epub 2007 Jan 2. J Clin Endocrinol Metab. 2007. PMID: 17200173
Association of single-nucleotide polymorphisms in MTMR9 gene with obesity.
Yanagiya T, Tanabe A, Iida A, Saito S, Sekine A, Takahashi A, Tsunoda T, Kamohara S, Nakata Y, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Masuzaki H, Yoneda M, Nakajima A, Miyazaki S, Tokunaga K, Kawamoto M, Funahashi T, Hamaguchi K, Tanaka K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Nakao K, Sakata T, Matsuzawa Y, Kamatani N, Nakamura Y, Hotta K. Yanagiya T, et al. Among authors: hotta k. Hum Mol Genet. 2007 Dec 15;16(24):3017-26. doi: 10.1093/hmg/ddm260. Epub 2007 Sep 12. Hum Mol Genet. 2007. PMID: 17855449
Variations in the FTO gene are associated with severe obesity in the Japanese.
Hotta K, Nakata Y, Matsuo T, Kamohara S, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Masuzaki H, Yoneda M, Nakajima A, Miyazaki S, Tokunaga K, Kawamoto M, Funahashi T, Hamaguchi K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Nakao K, Sakata T, Matsuzawa Y, Tanaka K, Kamatani N, Nakamura Y. Hotta K, et al. J Hum Genet. 2008;53(6):546-553. doi: 10.1007/s10038-008-0283-1. Epub 2008 Apr 1. J Hum Genet. 2008. PMID: 18379722 Free PMC article.
Association between PPARGC1A polymorphisms and the occurrence of nonalcoholic fatty liver disease (NAFLD).
Yoneda M, Hotta K, Nozaki Y, Endo H, Uchiyama T, Mawatari H, Iida H, Kato S, Hosono K, Fujita K, Yoneda K, Takahashi H, Kirikoshi H, Kobayashi N, Inamori M, Abe Y, Kubota K, Saito S, Maeyama S, Wada K, Nakajima A. Yoneda M, et al. Among authors: hotta k. BMC Gastroenterol. 2008 Jun 27;8:27. doi: 10.1186/1471-230X-8-27. BMC Gastroenterol. 2008. PMID: 18588668 Free PMC article.
INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese.
Hotta K, Nakamura M, Nakata Y, Matsuo T, Kamohara S, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Masuzaki H, Yoneda M, Nakajima A, Miyazaki S, Tokunaga K, Kawamoto M, Funahashi T, Hamaguchi K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Nakao K, Sakata T, Matsuzawa Y, Tanaka K, Kamatani N, Nakamura Y. Hotta K, et al. J Hum Genet. 2008;53(9):857-862. doi: 10.1007/s10038-008-0317-8. Epub 2008 Jul 10. J Hum Genet. 2008. PMID: 18615239 Free PMC article.
Screening of 336 single-nucleotide polymorphisms in 85 obesity-related genes revealed McKusick-Kaufman syndrome gene variants are associated with metabolic syndrome.
Hotta K, Nakamura T, Takasaki J, Takahashi H, Takahashi A, Nakata Y, Kamohara S, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Masuzaki H, Yoneda M, Nakajima A, Funahashi T, Miyazaki S, Tokunaga K, Hamaguchi K, Tanaka K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Nakao K, Sakata T, Matsuzawa Y, Kamatani N, Nakamura Y. Hotta K, et al. J Hum Genet. 2009 Apr;54(4):230-5. doi: 10.1038/jhg.2009.16. Epub 2009 Feb 27. J Hum Genet. 2009. PMID: 19247371
Serum ferritin is a clinical biomarker in Japanese patients with nonalcoholic steatohepatitis (NASH) independent of HFE gene mutation.
Yoneda M, Nozaki Y, Endo H, Mawatari H, Iida H, Fujita K, Yoneda K, Takahashi H, Kirikoshi H, Inamori M, Kobayashi N, Kubota K, Saito S, Maeyama S, Hotta K, Nakajima A. Yoneda M, et al. Among authors: hotta k. Dig Dis Sci. 2010 Mar;55(3):808-14. doi: 10.1007/s10620-009-0771-y. Epub 2009 Mar 7. Dig Dis Sci. 2010. PMID: 19267193
Association between angiotensin II type 1 receptor polymorphisms and the occurrence of nonalcoholic fatty liver disease.
Yoneda M, Hotta K, Nozaki Y, Endo H, Uchiyama T, Mawatari H, Iida H, Kato S, Fujita K, Takahashi H, Kirikoshi H, Kobayashi N, Inamori M, Abe Y, Kubota K, Saito S, Maeyama S, Wada K, Nakajima A. Yoneda M, et al. Among authors: hotta k. Liver Int. 2009 Aug;29(7):1078-85. doi: 10.1111/j.1478-3231.2009.01988.x. Epub 2009 Mar 3. Liver Int. 2009. PMID: 19302184
1,543 results