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Proarrhythmia in a non-failing murine model of cardiac-specific Na+/Ca 2+ exchanger overexpression: whole heart and cellular mechanisms.
Pott C, Muszynski A, Ruhe M, Bögeholz N, Schulte JS, Milberg P, Mönnig G, Fabritz L, Goldhaber JI, Breithardt G, Schmitz W, Philipson KD, Eckardt L, Kirchhof P, Müller FU. Pott C, et al. Among authors: muller fu. Basic Res Cardiol. 2012 Mar;107(2):247. doi: 10.1007/s00395-012-0247-7. Epub 2012 Feb 11. Basic Res Cardiol. 2012. PMID: 22327339 Free PMC article.
Triggered activity in atrial myocytes is influenced by Na+/Ca2+ exchanger activity in genetically altered mice.
Bögeholz N, Pauls P, Kaese S, Schulte JS, Lemoine MD, Dechering DG, Frommeyer G, Goldhaber JI, Seidl MD, Kirchhefer U, Eckardt L, Müller FU, Pott C. Bögeholz N, et al. Among authors: muller fu. J Mol Cell Cardiol. 2016 Dec;101:106-115. doi: 10.1016/j.yjmcc.2016.11.004. Epub 2016 Nov 9. J Mol Cell Cardiol. 2016. PMID: 27838371 Free PMC article.
The Effects of SEA0400 on Ca2+ Transient Amplitude and Proarrhythmia Depend on the Na+/Ca2+ Exchanger Expression Level in Murine Models.
Bögeholz N, Schulte JS, Kaese S, Bauer BK, Pauls P, Dechering DG, Frommeyer G, Goldhaber JI, Kirchhefer U, Eckardt L, Pott C, Müller FU. Bögeholz N, et al. Among authors: muller fu. Front Pharmacol. 2017 Sep 21;8:649. doi: 10.3389/fphar.2017.00649. eCollection 2017. Front Pharmacol. 2017. PMID: 28983248 Free PMC article.
Distinct Occurrence of Proarrhythmic Afterdepolarizations in Atrial Versus Ventricular Cardiomyocytes: Implications for Translational Research on Atrial Arrhythmia.
Bögeholz N, Pauls P, Dechering DG, Frommeyer G, Goldhaber JI, Pott C, Eckardt L, Müller FU, Schulte JS. Bögeholz N, et al. Among authors: muller fu. Front Pharmacol. 2018 Aug 21;9:933. doi: 10.3389/fphar.2018.00933. eCollection 2018. Front Pharmacol. 2018. PMID: 30186171 Free PMC article.
First report on an inotropic peptide activating tetrodotoxin-sensitive, "neuronal" sodium currents in the heart.
Kirchhof P, Tal T, Fabritz L, Klimas J, Nesher N, Schulte JS, Ehling P, Kanyshkova T, Budde T, Nikol S, Fortmueller L, Stallmeyer B, Müller FU, Schulze-Bahr E, Schmitz W, Zlotkin E, Kirchhefer U. Kirchhof P, et al. Among authors: muller fu. Circ Heart Fail. 2015 Jan;8(1):79-88. doi: 10.1161/CIRCHEARTFAILURE.113.001066. Epub 2014 Nov 25. Circ Heart Fail. 2015. PMID: 25424392 Free article.
Sphingosine-1-Phosphate Receptor 1 Regulates Cardiac Function by Modulating Ca2+ Sensitivity and Na+/H+ Exchange and Mediates Protection by Ischemic Preconditioning.
Keul P, van Borren MM, Ghanem A, Müller FU, Baartscheer A, Verkerk AO, Stümpel F, Schulte JS, Hamdani N, Linke WA, van Loenen P, Matus M, Schmitz W, Stypmann J, Tiemann K, Ravesloot JH, Alewijnse AE, Hermann S, Spijkers LJ, Hiller KH, Herr D, Heusch G, Schäfers M, Peters SL, Chun J, Levkau B. Keul P, et al. Among authors: muller fu. J Am Heart Assoc. 2016 May 20;5(5):e003393. doi: 10.1161/JAHA.116.003393. J Am Heart Assoc. 2016. PMID: 27207969 Free PMC article.
124 results