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Proarrhythmia as a class effect of quinolones: increased dispersion of repolarization and triangulation of action potential predict torsades de pointes.
Milberg P, Hilker E, Ramtin S, Cakir Y, Stypmann J, Engelen MA, Mönnig G, Osada N, Breithardt G, Haverkamp W, Eckardt L. Milberg P, et al. Among authors: osada n. J Cardiovasc Electrophysiol. 2007 Jun;18(6):647-54. doi: 10.1111/j.1540-8167.2007.00793.x. Epub 2007 Mar 28. J Cardiovasc Electrophysiol. 2007. PMID: 17388913
Antiarrhythmic effects of free polyunsaturated fatty acids in an experimental model of LQT2 and LQT3 due to suppression of early afterdepolarizations and reduction of spatial and temporal dispersion of repolarization.
Milberg P, Frommeyer G, Kleideiter A, Fischer A, Osada N, Breithardt G, Fehr M, Eckardt L. Milberg P, et al. Among authors: osada n. Heart Rhythm. 2011 Sep;8(9):1492-500. doi: 10.1016/j.hrthm.2011.03.058. Epub 2011 Apr 1. Heart Rhythm. 2011. PMID: 21459164
A new mechanism preventing proarrhythmia in chronic heart failure: rapid phase-III repolarization explains the low proarrhythmic potential of amiodarone in contrast to sotalol in a model of pacing-induced heart failure.
Frommeyer G, Milberg P, Witte P, Stypmann J, Koopmann M, Lücke M, Osada N, Breithardt G, Fehr M, Eckardt L. Frommeyer G, et al. Among authors: osada n. Eur J Heart Fail. 2011 Oct;13(10):1060-9. doi: 10.1093/eurjhf/hfr107. Epub 2011 Aug 25. Eur J Heart Fail. 2011. PMID: 21873342 Free article.
G-CSF therapy reduces myocardial repolarization reserve in the presence of increased arteriogenesis, angiogenesis and connexin 43 expression in an experimental model of pacing-induced heart failure.
Milberg P, Klocke R, Frommeyer G, Quang TH, Dieks K, Stypmann J, Osada N, Kuhlmann M, Fehr M, Milting H, Nikol S, Waltenberger J, Breithardt G, Eckardt L. Milberg P, et al. Among authors: osada n. Basic Res Cardiol. 2011 Nov;106(6):995-1008. doi: 10.1007/s00395-011-0230-8. Epub 2011 Nov 10. Basic Res Cardiol. 2011. PMID: 22072114
356 results