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Phase 1 clinical trial of the novel proteasome inhibitor marizomib with the histone deacetylase inhibitor vorinostat in patients with melanoma, pancreatic and lung cancer based on in vitro assessments of the combination.
Millward M, Price T, Townsend A, Sweeney C, Spencer A, Sukumaran S, Longenecker A, Lee L, Lay A, Sharma G, Gemmill RM, Drabkin HA, Lloyd GK, Neuteboom ST, McConkey DJ, Palladino MA, Spear MA. Millward M, et al. Among authors: mcconkey dj. Invest New Drugs. 2012 Dec;30(6):2303-17. doi: 10.1007/s10637-011-9766-6. Epub 2011 Nov 12. Invest New Drugs. 2012. PMID: 22080430 Clinical Trial.
A phase I surrogate endpoint study of SU6668 in patients with solid tumors.
Xiong HQ, Herbst R, Faria SC, Scholz C, Davis D, Jackson EF, Madden T, McConkey D, Hicks M, Hess K, Charnsangavej CA, Abbruzzese JL. Xiong HQ, et al. Invest New Drugs. 2004 Nov;22(4):459-66. doi: 10.1023/B:DRUG.0000036688.96453.8d. Invest New Drugs. 2004. PMID: 15292716 Clinical Trial.
Novel therapies for pancreatic adenocarcinoma.
Pino SM, Xiong HQ, McConkey D, Abbruzzese JL. Pino SM, et al. Curr Gastroenterol Rep. 2004 Apr;6(2):119-25. doi: 10.1007/s11894-004-0038-x. Curr Gastroenterol Rep. 2004. PMID: 15191689 Review.
Effects of mTOR inhibitor everolimus (RAD001) on bladder cancer cells.
Chiong E, Lee IL, Dadbin A, Sabichi AL, Harris L, Urbauer D, McConkey DJ, Dickstein RJ, Cheng T, Grossman HB. Chiong E, et al. Among authors: mcconkey dj. Clin Cancer Res. 2011 May 1;17(9):2863-73. doi: 10.1158/1078-0432.CCR-09-3202. Epub 2011 Mar 17. Clin Cancer Res. 2011. PMID: 21415218 Free PMC article.
290 results