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A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13.
Cho MH, Castaldi PJ, Wan ES, Siedlinski M, Hersh CP, Demeo DL, Himes BE, Sylvia JS, Klanderman BJ, Ziniti JP, Lange C, Litonjua AA, Sparrow D, Regan EA, Make BJ, Hokanson JE, Murray T, Hetmanski JB, Pillai SG, Kong X, Anderson WH, Tal-Singer R, Lomas DA, Coxson HO, Edwards LD, MacNee W, Vestbo J, Yates JC, Agusti A, Calverley PM, Celli B, Crim C, Rennard S, Wouters E, Bakke P, Gulsvik A, Crapo JD, Beaty TH, Silverman EK; ICGN Investigators; ECLIPSE Investigators; COPDGene Investigators. Cho MH, et al. Among authors: demeo dl. Hum Mol Genet. 2012 Feb 15;21(4):947-57. doi: 10.1093/hmg/ddr524. Epub 2011 Nov 11. Hum Mol Genet. 2012. PMID: 22080838 Free PMC article.
The SERPINE2 gene is associated with chronic obstructive pulmonary disease.
Demeo DL, Mariani TJ, Lange C, Srisuma S, Litonjua AA, Celedon JC, Lake SL, Reilly JJ, Chapman HA, Mecham BH, Haley KJ, Sylvia JS, Sparrow D, Spira AE, Beane J, Pinto-Plata V, Speizer FE, Shapiro SD, Weiss ST, Silverman EK. Demeo DL, et al. Am J Hum Genet. 2006 Feb;78(2):253-64. doi: 10.1086/499828. Epub 2005 Dec 15. Am J Hum Genet. 2006. PMID: 16358219 Free PMC article.
Genetic determinants of emphysema distribution in the national emphysema treatment trial.
DeMeo DL, Hersh CP, Hoffman EA, Litonjua AA, Lazarus R, Sparrow D, Benditt JO, Criner G, Make B, Martinez FJ, Scanlon PD, Sciurba FC, Utz JP, Reilly JJ, Silverman EK. DeMeo DL, et al. Am J Respir Crit Care Med. 2007 Jul 1;176(1):42-8. doi: 10.1164/rccm.200612-1797OC. Epub 2007 Mar 15. Am J Respir Crit Care Med. 2007. PMID: 17363767 Free PMC article. Clinical Trial.
Variants in FAM13A are associated with chronic obstructive pulmonary disease.
Cho MH, Boutaoui N, Klanderman BJ, Sylvia JS, Ziniti JP, Hersh CP, DeMeo DL, Hunninghake GM, Litonjua AA, Sparrow D, Lange C, Won S, Murphy JR, Beaty TH, Regan EA, Make BJ, Hokanson JE, Crapo JD, Kong X, Anderson WH, Tal-Singer R, Lomas DA, Bakke P, Gulsvik A, Pillai SG, Silverman EK. Cho MH, et al. Among authors: demeo dl. Nat Genet. 2010 Mar;42(3):200-2. doi: 10.1038/ng.535. Epub 2010 Feb 21. Nat Genet. 2010. PMID: 20173748 Free PMC article.
335 results