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A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13.
Cho MH, Castaldi PJ, Wan ES, Siedlinski M, Hersh CP, Demeo DL, Himes BE, Sylvia JS, Klanderman BJ, Ziniti JP, Lange C, Litonjua AA, Sparrow D, Regan EA, Make BJ, Hokanson JE, Murray T, Hetmanski JB, Pillai SG, Kong X, Anderson WH, Tal-Singer R, Lomas DA, Coxson HO, Edwards LD, MacNee W, Vestbo J, Yates JC, Agusti A, Calverley PM, Celli B, Crim C, Rennard S, Wouters E, Bakke P, Gulsvik A, Crapo JD, Beaty TH, Silverman EK; ICGN Investigators; ECLIPSE Investigators; COPDGene Investigators. Cho MH, et al. Among authors: siedlinski m. Hum Mol Genet. 2012 Feb 15;21(4):947-57. doi: 10.1093/hmg/ddr524. Epub 2011 Nov 11. Hum Mol Genet. 2012. PMID: 22080838 Free PMC article.
Genome-wide association study of smoking behaviours in patients with COPD.
Siedlinski M, Cho MH, Bakke P, Gulsvik A, Lomas DA, Anderson W, Kong X, Rennard SI, Beaty TH, Hokanson JE, Crapo JD, Silverman EK; COPDGene Investigators; ECLIPSE Investigators. Siedlinski M, et al. Thorax. 2011 Oct;66(10):894-902. doi: 10.1136/thoraxjnl-2011-200154. Epub 2011 Jun 16. Thorax. 2011. PMID: 21685187 Free PMC article. Clinical Trial.
Dissecting direct and indirect genetic effects on chronic obstructive pulmonary disease (COPD) susceptibility.
Siedlinski M, Tingley D, Lipman PJ, Cho MH, Litonjua AA, Sparrow D, Bakke P, Gulsvik A, Lomas DA, Anderson W, Kong X, Rennard SI, Beaty TH, Hokanson JE, Crapo JD, Lange C, Silverman EK; COPDGene and ECLIPSE Investigators. Siedlinski M, et al. Hum Genet. 2013 Apr;132(4):431-41. doi: 10.1007/s00439-012-1262-3. Epub 2013 Jan 9. Hum Genet. 2013. PMID: 23299987 Free PMC article. Clinical Trial.
Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels.
Portelli MA, Siedlinski M, Stewart CE, Postma DS, Nieuwenhuis MA, Vonk JM, Nurnberg P, Altmuller J, Moffatt MF, Wardlaw AJ, Parker SG, Connolly MJ, Koppelman GH, Sayers I. Portelli MA, et al. Among authors: siedlinski m. FASEB J. 2014 Feb;28(2):923-34. doi: 10.1096/fj.13-240879. Epub 2013 Nov 18. FASEB J. 2014. PMID: 24249636 Free PMC article.
Combining genomewide association study and lung eQTL analysis provides evidence for novel genes associated with asthma.
Nieuwenhuis MA, Siedlinski M, van den Berge M, Granell R, Li X, Niens M, van der Vlies P, Altmüller J, Nürnberg P, Kerkhof M, van Schayck OC, Riemersma RA, van der Molen T, de Monchy JG, Bossé Y, Sandford A, Bruijnzeel-Koomen CA, Gerth van Wijk R, Ten Hacken NH, Timens W, Boezen HM, Henderson J, Kabesch M, Vonk JM, Postma DS, Koppelman GH. Nieuwenhuis MA, et al. Among authors: siedlinski m. Allergy. 2016 Dec;71(12):1712-1720. doi: 10.1111/all.12990. Epub 2016 Aug 22. Allergy. 2016. PMID: 27439200 Free PMC article.
Multidrug resistance-associated protein-1 (MRP1) genetic variants, MRP1 protein levels and severity of COPD.
Budulac SE, Postma DS, Hiemstra PS, Kunz LI, Siedlinski M, Smit HA, Vonk JM, Rutgers B, Timens W, Boezen HM; Groningen Leiden Universities Corticosteroids in Obstructive Lung Disease (GLUCOLD) study group. Budulac SE, et al. Among authors: siedlinski m. Respir Res. 2010 May 20;11(1):60. doi: 10.1186/1465-9921-11-60. Respir Res. 2010. PMID: 20487524 Free PMC article.
57 results