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The combination of TPL2 knockdown and TNFα causes synthetic lethality via caspase-8 activation in human carcinoma cell lines.
Serebrennikova OB, Paraskevopoulou MD, Aguado-Fraile E, Taraslia V, Ren W, Thapa G, Roper J, Du K, Croce CM, Tsichlis PN. Serebrennikova OB, et al. Among authors: tsichlis pn. Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):14039-14048. doi: 10.1073/pnas.1901465116. Epub 2019 Jun 25. Proc Natl Acad Sci U S A. 2019. PMID: 31239343 Free PMC article.
Tcl1 enhances Akt kinase activity and mediates its nuclear translocation.
Pekarsky Y, Koval A, Hallas C, Bichi R, Tresini M, Malstrom S, Russo G, Tsichlis P, Croce CM. Pekarsky Y, et al. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3028-33. doi: 10.1073/pnas.97.7.3028. Proc Natl Acad Sci U S A. 2000. PMID: 10716693 Free PMC article.
225 results