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Page 1
Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia.
Skrtić M, Sriskanthadevan S, Jhas B, Gebbia M, Wang X, Wang Z, Hurren R, Jitkova Y, Gronda M, Maclean N, Lai CK, Eberhard Y, Bartoszko J, Spagnuolo P, Rutledge AC, Datti A, Ketela T, Moffat J, Robinson BH, Cameron JH, Wrana J, Eaves CJ, Minden MD, Wang JC, Dick JE, Humphries K, Nislow C, Giaever G, Schimmer AD. Skrtić M, et al. Among authors: humphries k. Cancer Cell. 2011 Nov 15;20(5):674-88. doi: 10.1016/j.ccr.2011.10.015. Cancer Cell. 2011. PMID: 22094260 Free PMC article.
Epigenetic and functional changes imposed by NUP98-HOXA9 in a genetically engineered model of chronic myeloid leukemia progression.
Sloma I, Beer P, Desterke C, Bulaeva E, Bilenky M, Carles A, Moksa M, Raghuram K, Brimacombe C, Lambie K, Turhan AG, Wagner-Ballon O, Gaulard P, Humphries K, Hirst M, Eaves CJ. Sloma I, et al. Among authors: humphries k. Haematologica. 2021 Mar 1;106(3):881-885. doi: 10.3324/haematol.2020.249243. Haematologica. 2021. PMID: 32499242 Free PMC article. No abstract available.
Aldehyde dehydrogenases in acute myeloid leukemia.
Smith C, Gasparetto M, Humphries K, Pollyea DA, Vasiliou V, Jordan CT. Smith C, et al. Among authors: humphries k. Ann N Y Acad Sci. 2014 Mar;1310:58-68. doi: 10.1111/nyas.12414. Ann N Y Acad Sci. 2014. PMID: 24641679 Review.
GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo.
Pabst C, Bergeron A, Lavallée VP, Yeh J, Gendron P, Norddahl GL, Krosl J, Boivin I, Deneault E, Simard J, Imren S, Boucher G, Eppert K, Herold T, Bohlander SK, Humphries K, Lemieux S, Hébert J, Sauvageau G, Barabé F. Pabst C, et al. Among authors: humphries k. Blood. 2016 Apr 21;127(16):2018-27. doi: 10.1182/blood-2015-11-683649. Epub 2016 Feb 1. Blood. 2016. PMID: 26834243 Free article.
RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity.
Cellot S, Hope KJ, Chagraoui J, Sauvageau M, Deneault É, MacRae T, Mayotte N, Wilhelm BT, Landry JR, Ting SB, Krosl J, Humphries K, Thompson A, Sauvageau G. Cellot S, et al. Among authors: humphries k. Blood. 2013 Aug 29;122(9):1545-55. doi: 10.1182/blood-2013-04-496281. Epub 2013 Jun 18. Blood. 2013. PMID: 23777767 Free PMC article.
CBL exon 8/9 mutants activate the FLT3 pathway and cluster in core binding factor/11q deletion acute myeloid leukemia/myelodysplastic syndrome subtypes.
Reindl C, Quentmeier H, Petropoulos K, Greif PA, Benthaus T, Argiropoulos B, Mellert G, Vempati S, Duyster J, Buske C, Bohlander SK, Humphries KR, Hiddemann W, Spiekermann K. Reindl C, et al. Among authors: humphries kr. Clin Cancer Res. 2009 Apr 1;15(7):2238-47. doi: 10.1158/1078-0432.CCR-08-1325. Epub 2009 Mar 10. Clin Cancer Res. 2009. PMID: 19276253
Delineating MEIS1 cis-regulatory elements active in hematopoietic cells.
Xiang P, Wei W, Lo C, Rosten P, Hou J, Hoodless PA, Bilenky M, Bonifer C, Cockerill PN, Kirkpatrick A, Gottgens B, Hirst M, Humphries KR. Xiang P, et al. Among authors: humphries kr. Leukemia. 2014 Feb;28(2):433-6. doi: 10.1038/leu.2013.287. Epub 2013 Oct 7. Leukemia. 2014. PMID: 24097337 No abstract available.
400 results