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PPAR-δ is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically.
Dickey AS, Pineda VV, Tsunemi T, Liu PP, Miranda HC, Gilmore-Hall SK, Lomas N, Sampat KR, Buttgereit A, Torres MJ, Flores AL, Arreola M, Arbez N, Akimov SS, Gaasterland T, Lazarowski ER, Ross CA, Yeo GW, Sopher BL, Magnuson GK, Pinkerton AB, Masliah E, La Spada AR. Dickey AS, et al. Among authors: tsunemi t. Nat Med. 2016 Jan;22(1):37-45. doi: 10.1038/nm.4003. Epub 2015 Dec 7. Nat Med. 2016. PMID: 26642438 Free PMC article.
A Statement of the MDS on Biological Definition, Staging, and Classification of Parkinson's Disease.
Cardoso F, Goetz CG, Mestre TA, Sampaio C, Adler CH, Berg D, Bloem BR, Burn DJ, Fitts MS, Gasser T, Klein C, de Tijssen MAJ, Lang AE, Lim SY, Litvan I, Meissner WG, Mollenhauer B, Okubadejo N, Okun MS, Postuma RB, Svenningsson P, Tan LCS, Tsunemi T, Wahlstrom-Helgren S, Gershanik OS, Fung VSC, Trenkwalder C. Cardoso F, et al. Among authors: tsunemi t. Mov Disord. 2024 Feb;39(2):259-266. doi: 10.1002/mds.29683. Epub 2023 Dec 13. Mov Disord. 2024. PMID: 38093469 No abstract available.
Increased Lysosomal Exocytosis Induced by Lysosomal Ca2+ Channel Agonists Protects Human Dopaminergic Neurons from α-Synuclein Toxicity.
Tsunemi T, Perez-Rosello T, Ishiguro Y, Yoroisaka A, Jeon S, Hamada K, Rammonhan M, Wong YC, Xie Z, Akamatsu W, Mazzulli JR, Surmeier DJ, Hattori N, Krainc D. Tsunemi T, et al. J Neurosci. 2019 Jul 17;39(29):5760-5772. doi: 10.1523/JNEUROSCI.3085-18.2019. Epub 2019 May 16. J Neurosci. 2019. PMID: 31097622 Free PMC article.
99 results