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774 results

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Design, synthesis, and biological evaluation of novel (1-thioxo-1,2,3,4-tetrahydro-β-carbolin-9-yl)acetic acids as selective inhibitors for AKR1B1.
Minehira D, Takeda D, Urata H, Kato A, Adachi I, Wang X, Matsuya Y, Sugimoto K, Takemura M, Endo S, Matsunaga T, Hara A, Koseki J, Narukawa K, Hirono S, Toyooka N. Minehira D, et al. Among authors: adachi i. Bioorg Med Chem. 2012 Jan 1;20(1):356-67. doi: 10.1016/j.bmc.2011.10.073. Epub 2011 Nov 3. Bioorg Med Chem. 2012. PMID: 22104435
6,7-Dihydroxy-4-phenylcoumarin as inhibitor of aldose reductase 2.
Kato A, Kobayashi K, Narukawa K, Minoshima Y, Adachi I, Hirono S, Nash RJ. Kato A, et al. Among authors: adachi i. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5630-3. doi: 10.1016/j.bmcl.2010.08.038. Epub 2010 Aug 12. Bioorg Med Chem Lett. 2010. PMID: 20805028
Synthesis and biological evaluation of N-(2-fluorophenyl)-2β-deoxyfuconojirimycin acetamide as a potent inhibitor for α-l-fucosidases.
Kato A, Okaki T, Ifuku S, Sato K, Hirokami Y, Iwaki R, Kamori A, Nakagawa S, Adachi I, Kiria PG, Onomura O, Minato D, Sugimoto K, Matsuya Y, Toyooka N. Kato A, et al. Among authors: adachi i. Bioorg Med Chem. 2013 Nov 1;21(21):6565-73. doi: 10.1016/j.bmc.2013.08.028. Epub 2013 Aug 24. Bioorg Med Chem. 2013. PMID: 24026016
Design and Synthesis of Labystegines, Hybrid Iminosugars from LAB and Calystegine, as Inhibitors of Intestinal α-Glucosidases: Binding Conformation and Interaction for ntSI.
Kato A, Zhang ZL, Wang HY, Jia YM, Yu CY, Kinami K, Hirokami Y, Tsuji Y, Adachi I, Nash RJ, Fleet GW, Koseki J, Nakagome I, Hirono S. Kato A, et al. Among authors: adachi i. J Org Chem. 2015 May 1;80(9):4501-15. doi: 10.1021/acs.joc.5b00342. Epub 2015 Apr 13. J Org Chem. 2015. PMID: 25843107
774 results