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Page 1
Inhibition of Notch3 signalling induces rhabdomyosarcoma cell differentiation promoting p38 phosphorylation and p21(Cip1) expression and hampers tumour cell growth in vitro and in vivo.
Raimondi L, Ciarapica R, De Salvo M, Verginelli F, Gueguen M, Martini C, De Sio L, Cortese G, Locatelli M, Dang TP, Carlesso N, Miele L, Stifani S, Limon I, Locatelli F, Rota R. Raimondi L, et al. Among authors: verginelli f. Cell Death Differ. 2012 May;19(5):871-81. doi: 10.1038/cdd.2011.171. Epub 2011 Nov 25. Cell Death Differ. 2012. PMID: 22117196 Free PMC article.
Hyper-activation of Notch3 amplifies the proliferative potential of rhabdomyosarcoma cells.
De Salvo M, Raimondi L, Vella S, Adesso L, Ciarapica R, Verginelli F, Pannuti A, Citti A, Boldrini R, Milano GM, Cacchione A, Ferrari A, Collini P, Rosolen A, Bisogno G, Alaggio R, Inserra A, Locatelli M, Stifani S, Screpanti I, Miele L, Locatelli F, Rota R. De Salvo M, et al. Among authors: verginelli f. PLoS One. 2014 May 5;9(5):e96238. doi: 10.1371/journal.pone.0096238. eCollection 2014. PLoS One. 2014. PMID: 24797362 Free PMC article.
The Polycomb group (PcG) protein EZH2 supports the survival of PAX3-FOXO1 alveolar rhabdomyosarcoma by repressing FBXO32 (Atrogin1/MAFbx).
Ciarapica R, De Salvo M, Carcarino E, Bracaglia G, Adesso L, Leoncini PP, Dall'Agnese A, Walters ZS, Verginelli F, De Sio L, Boldrini R, Inserra A, Bisogno G, Rosolen A, Alaggio R, Ferrari A, Collini P, Locatelli M, Stifani S, Screpanti I, Rutella S, Yu Q, Marquez VE, Shipley J, Valente S, Mai A, Miele L, Puri PL, Locatelli F, Palacios D, Rota R. Ciarapica R, et al. Among authors: verginelli f. Oncogene. 2014 Aug 7;33(32):4173-84. doi: 10.1038/onc.2013.471. Epub 2013 Nov 11. Oncogene. 2014. PMID: 24213577
Pharmacological inhibition of EZH2 as a promising differentiation therapy in embryonal RMS.
Ciarapica R, Carcarino E, Adesso L, De Salvo M, Bracaglia G, Leoncini PP, Dall'agnese A, Verginelli F, Milano GM, Boldrini R, Inserra A, Stifani S, Screpanti I, Marquez VE, Valente S, Mai A, Puri PL, Locatelli F, Palacios D, Rota R. Ciarapica R, et al. Among authors: verginelli f. BMC Cancer. 2014 Feb 27;14:139. doi: 10.1186/1471-2407-14-139. BMC Cancer. 2014. PMID: 24575771 Free PMC article.
Deregulated expression of miR-26a and Ezh2 in rhabdomyosarcoma.
Ciarapica R, Russo G, Verginelli F, Raimondi L, Donfrancesco A, Rota R, Giordano A. Ciarapica R, et al. Among authors: verginelli f. Cell Cycle. 2009 Jan 1;8(1):172-5. doi: 10.4161/cc.8.1.7292. Epub 2009 Jan 30. Cell Cycle. 2009. PMID: 19106613 No abstract available.
An Arf/Rab cascade controls the growth and invasiveness of glioblastoma.
Kulasekaran G, Chaineau M, Piscopo VEC, Verginelli F, Fotouhi M, Girard M, Tang Y, Dali R, Lo R, Stifani S, McPherson PS. Kulasekaran G, et al. Among authors: verginelli f. J Cell Biol. 2021 Feb 1;220(2):e202004229. doi: 10.1083/jcb.202004229. J Cell Biol. 2021. PMID: 33443570 Free PMC article.
Transcription factors FOXG1 and Groucho/TLE promote glioblastoma growth.
Verginelli F, Perin A, Dali R, Fung KH, Lo R, Longatti P, Guiot MC, Del Maestro RF, Rossi S, di Porzio U, Stechishin O, Weiss S, Stifani S. Verginelli F, et al. Nat Commun. 2013;4:2956. doi: 10.1038/ncomms3956. Nat Commun. 2013. PMID: 24356439 Free PMC article.
72 results