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TREM-2 defends the liver against hepatocellular carcinoma through multifactorial protective mechanisms.
Esparza-Baquer A, Labiano I, Sharif O, Agirre-Lizaso A, Oakley F, Rodrigues PM, Zhuravleva E, O'Rourke CJ, Hijona E, Jimenez-Agüero R, Riaño I, Landa A, La Casta A, Zaki MYW, Munoz-Garrido P, Azkargorta M, Elortza F, Vogel A, Schabbauer G, Aspichueta P, Andersen JB, Knapp S, Mann DA, Bujanda L, Banales JM, Perugorria MJ. Esparza-Baquer A, et al. Among authors: perugorria mj. Gut. 2021 Jul;70(7):1345-1361. doi: 10.1136/gutjnl-2019-319227. Epub 2020 Sep 9. Gut. 2021. PMID: 32907830 Free PMC article.
Non-parenchymal TREM-2 protects the liver from immune-mediated hepatocellular damage.
Perugorria MJ, Esparza-Baquer A, Oakley F, Labiano I, Korosec A, Jais A, Mann J, Tiniakos D, Santos-Laso A, Arbelaiz A, Gawish R, Sampedro A, Fontanellas A, Hijona E, Jimenez-Agüero R, Esterbauer H, Stoiber D, Bujanda L, Banales JM, Knapp S, Sharif O, Mann DA. Perugorria MJ, et al. Gut. 2019 Mar;68(3):533-546. doi: 10.1136/gutjnl-2017-314107. Epub 2018 Jan 27. Gut. 2019. PMID: 29374630 Free PMC article.
TREM-2 plays a protective role in cholestasis by acting as a negative regulator of inflammation.
Labiano I, Agirre-Lizaso A, Olaizola P, Echebarria A, Huici-Izagirre M, Olaizola I, Esparza-Baquer A, Sharif O, Hijona E, Milkiewicz P, Milkiewicz M, González-Romero F, Aspichueta P, Monte MJ, Marin JJG, Vucur M, Luedde T, Marzioni M, Mann DA, Bujanda L, Rodrigues PM, Banales JM, Perugorria MJ. Labiano I, et al. Among authors: perugorria mj. J Hepatol. 2022 Oct;77(4):991-1004. doi: 10.1016/j.jhep.2022.05.044. Epub 2022 Jun 22. J Hepatol. 2022. PMID: 35750136 Free article.
MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis.
Fernández-Ramos D, Fernández-Tussy P, Lopitz-Otsoa F, Gutiérrez-de-Juan V, Navasa N, Barbier-Torres L, Zubiete-Franco I, Simón J, Fernández AF, Arbelaiz A, Aransay AM, Lavín JL, Beraza N, Perugorria MJ, Banales JM, Villa E, Fraga MF, Anguita J, Avila MA, Berasain C, Iruzibieta P, Crespo J, Lu SC, Varela-Rey M, Mato JM, Delgado TC, Martínez-Chantar ML. Fernández-Ramos D, et al. Among authors: perugorria mj. Cell Death Dis. 2018 Sep 20;9(10):958. doi: 10.1038/s41419-018-1014-y. Cell Death Dis. 2018. PMID: 30237481 Free PMC article.
Polycystic liver diseases: advanced insights into the molecular mechanisms.
Perugorria MJ, Masyuk TV, Marin JJ, Marzioni M, Bujanda L, LaRusso NF, Banales JM. Perugorria MJ, et al. Nat Rev Gastroenterol Hepatol. 2014 Dec;11(12):750-61. doi: 10.1038/nrgastro.2014.155. Epub 2014 Sep 30. Nat Rev Gastroenterol Hepatol. 2014. PMID: 25266109 Free PMC article. Review.
73 results