Karki S - Search Results

1

A novel bispecific antibody format enables simultaneous bivalent and monovalent co-engagement of distinct target antigens.

Moore GL, Bautista C, Pong E, Nguyen DH, Jacinto J, Eivazi A, Muchhal US, Karki S, Chu SY, Lazar GA. Moore GL, et al. Among authors: karki s. MAbs. 2011 Nov-Dec;3(6):546-57. doi: 10.4161/mabs.3.6.18123. Epub 2011 Nov 1. MAbs. 2011. PMID: 22123055 Free PMC article.

2

Inhibition of B cell receptor-mediated activation of primary human B cells by coengagement of CD19 and FcgammaRIIb with Fc-engineered antibodies.

Chu SY, Vostiar I, Karki S, Moore GL, Lazar GA, Pong E, Joyce PF, Szymkowski DE, Desjarlais JR. Chu SY, et al. Among authors: karki s. Mol Immunol. 2008 Sep;45(15):3926-33. doi: 10.1016/j.molimm.2008.06.027. Epub 2008 Aug 8. Mol Immunol. 2008. PMID: 18691763

3

Engineered Fc variant antibodies with enhanced ability to recruit complement and mediate effector functions.

Moore GL, Chen H, Karki S, Lazar GA. Moore GL, et al. Among authors: karki s. MAbs. 2010 Mar-Apr;2(2):181-9. doi: 10.4161/mabs.2.2.11158. MAbs. 2010. PMID: 20150767 Free PMC article.

4

Engineered antibody Fc variants with enhanced effector function.

Lazar GA, Dang W, Karki S, Vafa O, Peng JS, Hyun L, Chan C, Chung HS, Eivazi A, Yoder SC, Vielmetter J, Carmichael DF, Hayes RJ, Dahiyat BI. Lazar GA, et al. Among authors: karki s. Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4005-10. doi: 10.1073/pnas.0508123103. Epub 2006 Mar 6. Proc Natl Acad Sci U S A. 2006. PMID: 16537476 Free PMC article.

5

A molecular immunology approach to antibody humanization and functional optimization.

Lazar GA, Desjarlais JR, Jacinto J, Karki S, Hammond PW. Lazar GA, et al. Among authors: karki s. Mol Immunol. 2007 Mar;44(8):1986-98. doi: 10.1016/j.molimm.2006.09.029. Epub 2006 Oct 31. Mol Immunol. 2007. PMID: 17079018

6

Optimization of antibody binding to FcgammaRIIa enhances macrophage phagocytosis of tumor cells.

Richards JO, Karki S, Lazar GA, Chen H, Dang W, Desjarlais JR. Richards JO, et al. Among authors: karki s. Mol Cancer Ther. 2008 Aug;7(8):2517-27. doi: 10.1158/1535-7163.MCT-08-0201. Mol Cancer Ther. 2008. PMID: 18723496

7

Potent in vitro and in vivo activity of an Fc-engineered anti-CD19 monoclonal antibody against lymphoma and leukemia.

Horton HM, Bernett MJ, Pong E, Peipp M, Karki S, Chu SY, Richards JO, Vostiar I, Joyce PF, Repp R, Desjarlais JR, Zhukovsky EA. Horton HM, et al. Among authors: karki s. Cancer Res. 2008 Oct 1;68(19):8049-57. doi: 10.1158/0008-5472.CAN-08-2268. Cancer Res. 2008. PMID: 18829563

8

Engineering fully human monoclonal antibodies from murine variable regions.

Bernett MJ, Karki S, Moore GL, Leung IW, Chen H, Pong E, Nguyen DH, Jacinto J, Zalevsky J, Muchhal US, Desjarlais JR, Lazar GA. Bernett MJ, et al. Among authors: karki s. J Mol Biol. 2010 Mar 12;396(5):1474-90. doi: 10.1016/j.jmb.2009.12.046. Epub 2010 Jan 4. J Mol Biol. 2010. PMID: 20045416

9

Fc-engineered anti-CD40 antibody enhances multiple effector functions and exhibits potent in vitro and in vivo antitumor activity against hematologic malignancies.

Horton HM, Bernett MJ, Peipp M, Pong E, Karki S, Chu SY, Richards JO, Chen H, Repp R, Desjarlais JR, Zhukovsky EA. Horton HM, et al. Among authors: karki s. Blood. 2010 Oct 21;116(16):3004-12. doi: 10.1182/blood-2010-01-265280. Epub 2010 Jul 8. Blood. 2010. PMID: 20616215 Free article.

10

The impact of Fc engineering on an anti-CD19 antibody: increased Fcgamma receptor affinity enhances B-cell clearing in nonhuman primates.

Zalevsky J, Leung IW, Karki S, Chu SY, Zhukovsky EA, Desjarlais JR, Carmichael DF, Lawrence CE. Zalevsky J, et al. Among authors: karki s. Blood. 2009 Apr 16;113(16):3735-43. doi: 10.1182/blood-2008-10-182048. Epub 2008 Dec 24. Blood. 2009. PMID: 19109559 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

724 results

Search Page

Filters