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Mice with cardiac overexpression of peroxisome proliferator-activated receptor γ have impaired repolarization and spontaneous fatal ventricular arrhythmias.
Morrow JP, Katchman A, Son NH, Trent CM, Khan R, Shiomi T, Huang H, Amin V, Lader JM, Vasquez C, Morley GE, D'Armiento J, Homma S, Goldberg IJ, Marx SO. Morrow JP, et al. Among authors: shiomi t. Circulation. 2011 Dec 20;124(25):2812-21. doi: 10.1161/CIRCULATIONAHA.111.056309. Epub 2011 Nov 28. Circulation. 2011. PMID: 22124376 Free PMC article.
Loss of secreted frizzled-related protein-1 leads to deterioration of cardiac function in mice and plays a role in human cardiomyopathy.
Sklepkiewicz P, Shiomi T, Kaur R, Sun J, Kwon S, Mercer B, Bodine P, Schermuly RT, George I, Schulze PC, D'Armiento JM. Sklepkiewicz P, et al. Among authors: shiomi t. Circ Heart Fail. 2015 Mar;8(2):362-72. doi: 10.1161/CIRCHEARTFAILURE.114.001274. Epub 2015 Feb 10. Circ Heart Fail. 2015. PMID: 25669938 Free PMC article.
473 results