Sleijfer S - Search Results

1

Sunitinib-induced systemic vasoconstriction in swine is endothelin mediated and does not involve nitric oxide or oxidative stress.

Kappers MH, de Beer VJ, Zhou Z, Danser AH, Sleijfer S, Duncker DJ, van den Meiracker AH, Merkus D. Kappers MH, et al. Among authors: sleijfer s. Hypertension. 2012 Jan;59(1):151-7. doi: 10.1161/HYPERTENSIONAHA.111.182220. Epub 2011 Nov 28. Hypertension. 2012. PMID: 22124432

2

Cardiovascular and renal toxicity during angiogenesis inhibition: clinical and mechanistic aspects.

Kappers MH, van Esch JH, Sleijfer S, Danser AH, van den Meiracker AH. Kappers MH, et al. Among authors: sleijfer s. J Hypertens. 2009 Dec;27(12):2297-309. doi: 10.1097/HJH.0b013e3283309b59. J Hypertens. 2009. PMID: 19680138 Review.

3

Hypertension induced by the tyrosine kinase inhibitor sunitinib is associated with increased circulating endothelin-1 levels.

Kappers MH, van Esch JH, Sluiter W, Sleijfer S, Danser AH, van den Meiracker AH. Kappers MH, et al. Among authors: sleijfer s. Hypertension. 2010 Oct;56(4):675-81. doi: 10.1161/HYPERTENSIONAHA.109.149690. Epub 2010 Aug 23. Hypertension. 2010. PMID: 20733093 Clinical Trial.

4

The vascular endothelial growth factor receptor inhibitor sunitinib causes a preeclampsia-like syndrome with activation of the endothelin system.

Kappers MH, Smedts FM, Horn T, van Esch JH, Sleijfer S, Leijten F, Wesseling S, Strevens H, Jan Danser AH, van den Meiracker AH. Kappers MH, et al. Among authors: sleijfer s. Hypertension. 2011 Aug;58(2):295-302. doi: 10.1161/HYPERTENSIONAHA.111.173559. Epub 2011 Jun 13. Hypertension. 2011. PMID: 21670421

5

Sunitinib-induced hypothyroidism is due to induction of type 3 deiodinase activity and thyroidal capillary regression.

Kappers MH, van Esch JH, Smedts FM, de Krijger RR, Eechoute K, Mathijssen RH, Sleijfer S, Leijten F, Danser AH, van den Meiracker AH, Visser TJ. Kappers MH, et al. Among authors: sleijfer s. J Clin Endocrinol Metab. 2011 Oct;96(10):3087-94. doi: 10.1210/jc.2011-1172. Epub 2011 Aug 3. J Clin Endocrinol Metab. 2011. PMID: 21816788

6

Re: Hypertension as a biomarker of efficacy in patients with metastatic renal cell carcinoma treated with sunitinib.

van den Meiracker AH, Danser AH, Sleijfer S, Kappers MH. van den Meiracker AH, et al. Among authors: sleijfer s. J Natl Cancer Inst. 2011 Oct 19;103(20):1557; author reply 1558. doi: 10.1093/jnci/djr328. Epub 2011 Aug 23. J Natl Cancer Inst. 2011. PMID: 21862728 No abstract available.

7

Treatment of hypertension and renal injury induced by the angiogenesis inhibitor sunitinib: preclinical study.

Lankhorst S, Kappers MH, van Esch JH, Smedts FM, Sleijfer S, Mathijssen RH, Baelde HJ, Danser AH, van den Meiracker AH. Lankhorst S, et al. Among authors: sleijfer s. Hypertension. 2014 Dec;64(6):1282-9. doi: 10.1161/HYPERTENSIONAHA.114.04187. Epub 2014 Sep 2. Hypertension. 2014. PMID: 25185126

8

Greater Sensitivity of Blood Pressure Than Renal Toxicity to Tyrosine Kinase Receptor Inhibition With Sunitinib.

Lankhorst S, Baelde HJ, Kappers MH, Smedts FM, Hansen A, Clahsen-van Groningen MC, Sleijfer S, Mathijssen RH, Danser AH, van den Meiracker AH. Lankhorst S, et al. Among authors: sleijfer s. Hypertension. 2015 Sep;66(3):543-9. doi: 10.1161/HYPERTENSIONAHA.115.05435. Epub 2015 Jul 20. Hypertension. 2015. PMID: 26195484

9

Bioanalytical method for the quantification of sunitinib and its n-desethyl metabolite SU12662 in human plasma by ultra performance liquid chromatography/tandem triple-quadrupole mass spectrometry.

de Bruijn P, Sleijfer S, Lam MH, Mathijssen RH, Wiemer EA, Loos WJ. de Bruijn P, et al. Among authors: sleijfer s. J Pharm Biomed Anal. 2010 Mar 11;51(4):934-41. doi: 10.1016/j.jpba.2009.10.020. Epub 2009 Oct 31. J Pharm Biomed Anal. 2010. PMID: 19931354

10

Decreased exposure to sunitinib due to concomitant administration of ifosfamide: results of a phase I and pharmacokinetic study on the combination of sunitinib and ifosfamide in patients with advanced solid malignancies.

Hamberg P, Steeghs N, Loos WJ, van de Biessen D, den Hollander M, Tascilar M, Verweij J, Gelderblom H, Sleijfer S. Hamberg P, et al. Among authors: sleijfer s. Br J Cancer. 2010 Jun 8;102(12):1699-706. doi: 10.1038/sj.bjc.6605696. Epub 2010 May 18. Br J Cancer. 2010. PMID: 20485286 Free PMC article. Clinical Trial.

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