Odlo K - Search Results

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Synthesis, biological evaluation and molecular modeling of 1,2,3-triazole analogs of combretastatin A-1.

Akselsen OW, Odlo K, Cheng JJ, Maccari G, Botta M, Hansen TV. Akselsen OW, et al. Among authors: odlo k. Bioorg Med Chem. 2012 Jan 1;20(1):234-42. doi: 10.1016/j.bmc.2011.11.010. Epub 2011 Nov 12. Bioorg Med Chem. 2012. PMID: 22137934

1,5-Disubstituted 1,2,3-triazoles as cis-restricted analogues of combretastatin A-4: Synthesis, molecular modeling and evaluation as cytotoxic agents and inhibitors of tubulin.

Odlo K, Hentzen J, dit Chabert JF, Ducki S, Gani OA, Sylte I, Skrede M, Flørenes VA, Hansen TV. Odlo K, et al. Bioorg Med Chem. 2008 May 1;16(9):4829-38. doi: 10.1016/j.bmc.2008.03.049. Epub 2008 Mar 23. Bioorg Med Chem. 2008. PMID: 18396050

1,2,3-triazole analogs of combretastatin A-4 as potential microtubule-binding agents.

Odlo K, Fournier-Dit-Chabert J, Ducki S, Gani OA, Sylte I, Hansen TV. Odlo K, et al. Bioorg Med Chem. 2010 Sep 15;18(18):6874-85. doi: 10.1016/j.bmc.2010.07.032. Epub 2010 Jul 17. Bioorg Med Chem. 2010. PMID: 20708408

Combretastatin A-4 and structurally related triazole analogues induce caspase-3 and reactive oxygen species-dependent cell death in PC12 cells.

Aziz G, Odlo K, Hansen TV, Paulsen RE, Mathisen GH. Aziz G, et al. Among authors: odlo k. Eur J Pharmacol. 2013 Mar 5;703(1-3):25-32. doi: 10.1016/j.ejphar.2013.01.043. Epub 2013 Feb 14. Eur J Pharmacol. 2013. PMID: 23416212

Contextual compound screening for improved therapeutic discovery.

Evensen L, Odlo K, Micklem DR, Littlewood-Evans A, Wood J, Kuzniewski C, Altmann KH, Hansen TV, Lorens JB. Evensen L, et al. Among authors: odlo k. Chembiochem. 2013 Dec 16;14(18):2512-8. doi: 10.1002/cbic.201300409. Epub 2013 Nov 12. Chembiochem. 2013. PMID: 24222525

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