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Als2-deficient mice exhibit disturbances in endosome trafficking associated with motor behavioral abnormalities.
Devon RS, Orban PC, Gerrow K, Barbieri MA, Schwab C, Cao LP, Helm JR, Bissada N, Cruz-Aguado R, Davidson TL, Witmer J, Metzler M, Lam CK, Tetzlaff W, Simpson EM, McCaffery JM, El-Husseini AE, Leavitt BR, Hayden MR. Devon RS, et al. Among authors: cao lp. Proc Natl Acad Sci U S A. 2006 Jun 20;103(25):9595-600. doi: 10.1073/pnas.0510197103. Epub 2006 Jun 12. Proc Natl Acad Sci U S A. 2006. PMID: 16769894 Free PMC article.
Behavioral deficits and striatal DA signaling in LRRK2 p.G2019S transgenic rats: a multimodal investigation including PET neuroimaging.
Walker MD, Volta M, Cataldi S, Dinelle K, Beccano-Kelly D, Munsie L, Kornelsen R, Mah C, Chou P, Co K, Khinda J, Mroczek M, Bergeron S, Yu K, Cao LP, Funk N, Ott T, Galter D, Riess O, Biskup S, Milnerwood AJ, Stoessl AJ, Farrer MJ, Sossi V. Walker MD, et al. Among authors: cao lp. J Parkinsons Dis. 2014;4(3):483-98. doi: 10.3233/JPD-140344. J Parkinsons Dis. 2014. PMID: 25000966
LRRK2 overexpression alters glutamatergic presynaptic plasticity, striatal dopamine tone, postsynaptic signal transduction, motor activity and memory.
Beccano-Kelly DA, Volta M, Munsie LN, Paschall SA, Tatarnikov I, Co K, Chou P, Cao LP, Bergeron S, Mitchell E, Han H, Melrose HL, Tapia L, Raymond LA, Farrer MJ, Milnerwood AJ. Beccano-Kelly DA, et al. Among authors: cao lp. Hum Mol Genet. 2015 Mar 1;24(5):1336-49. doi: 10.1093/hmg/ddu543. Epub 2014 Oct 24. Hum Mol Genet. 2015. PMID: 25343991
121 results