Shukla N - Search Results

1

Oncogene mutation profiling of pediatric solid tumors reveals significant subsets of embryonal rhabdomyosarcoma and neuroblastoma with mutated genes in growth signaling pathways.

Shukla N, Ameur N, Yilmaz I, Nafa K, Lau CY, Marchetti A, Borsu L, Barr FG, Ladanyi M. Shukla N, et al. Clin Cancer Res. 2012 Feb 1;18(3):748-57. doi: 10.1158/1078-0432.CCR-11-2056. Epub 2011 Dec 5. Clin Cancer Res. 2012. PMID: 22142829 Free PMC article.

2

TFE3 fusions activate MET signaling by transcriptional up-regulation, defining another class of tumors as candidates for therapeutic MET inhibition.

Tsuda M, Davis IJ, Argani P, Shukla N, McGill GG, Nagai M, Saito T, Laé M, Fisher DE, Ladanyi M. Tsuda M, et al. Among authors: shukla n. Cancer Res. 2007 Feb 1;67(3):919-29. doi: 10.1158/0008-5472.CAN-06-2855. Cancer Res. 2007. PMID: 17283122

3

Novel markers of subclinical disease for Ewing family tumors from gene expression profiling.

Cheung IY, Feng Y, Danis K, Shukla N, Meyers P, Ladanyi M, Cheung NK. Cheung IY, et al. Among authors: shukla n. Clin Cancer Res. 2007 Dec 1;13(23):6978-83. doi: 10.1158/1078-0432.CCR-07-1417. Clin Cancer Res. 2007. PMID: 18056173

4

High frequency of IDH-1 mutation links glioneuronal tumors with neuropil-like islands to diffuse astrocytomas.

Huse JT, Nafa K, Shukla N, Kastenhuber ER, Lavi E, Hedvat CV, Ladanyi M, Rosenblum MK. Huse JT, et al. Among authors: shukla n. Acta Neuropathol. 2011 Sep;122(3):367-9. doi: 10.1007/s00401-011-0855-6. Epub 2011 Jul 14. Acta Neuropathol. 2011. PMID: 21755347 Free PMC article. No abstract available.

5

Coactivation of receptor tyrosine kinases in malignant mesothelioma as a rationale for combination targeted therapy.

Brevet M, Shimizu S, Bott MJ, Shukla N, Zhou Q, Olshen AB, Rusch V, Ladanyi M. Brevet M, et al. Among authors: shukla n. J Thorac Oncol. 2011 May;6(5):864-74. doi: 10.1097/jto.0b013e318215a07d. J Thorac Oncol. 2011. PMID: 21774103 Free article.

6

Mutational inactivation of STAG2 causes aneuploidy in human cancer.

Solomon DA, Kim T, Diaz-Martinez LA, Fair J, Elkahloun AG, Harris BT, Toretsky JA, Rosenberg SA, Shukla N, Ladanyi M, Samuels Y, James CD, Yu H, Kim JS, Waldman T. Solomon DA, et al. Among authors: shukla n. Science. 2011 Aug 19;333(6045):1039-43. doi: 10.1126/science.1203619. Science. 2011. PMID: 21852505 Free PMC article.

7

Insulin-like growth factor 1 receptor as a therapeutic target in ewing sarcoma: lack of consistent upregulation or recurrent mutation and a review of the clinical trial literature.

O'Neill A, Shah N, Zitomersky N, Ladanyi M, Shukla N, Uren A, Loeb D, Toretsky J. O'Neill A, et al. Among authors: shukla n. Sarcoma. 2013;2013:450478. doi: 10.1155/2013/450478. Epub 2013 Jan 28. Sarcoma. 2013. PMID: 23431249 Free PMC article.

8

A recurrent neomorphic mutation in MYOD1 defines a clinically aggressive subset of embryonal rhabdomyosarcoma associated with PI3K-AKT pathway mutations.

Kohsaka S, Shukla N, Ameur N, Ito T, Ng CK, Wang L, Lim D, Marchetti A, Viale A, Pirun M, Socci ND, Qin LX, Sciot R, Bridge J, Singer S, Meyers P, Wexler LH, Barr FG, Dogan S, Fletcher JA, Reis-Filho JS, Ladanyi M. Kohsaka S, et al. Among authors: shukla n. Nat Genet. 2014 Jun;46(6):595-600. doi: 10.1038/ng.2969. Epub 2014 May 4. Nat Genet. 2014. PMID: 24793135 Free PMC article.

9

Integrating Genomics Into Clinical Pediatric Oncology Using the Molecular Tumor Board at the Memorial Sloan Kettering Cancer Center.

Ortiz MV, Kobos R, Walsh M, Slotkin EK, Roberts S, Berger MF, Hameed M, Solit D, Ladanyi M, Shukla N, Kentsis A. Ortiz MV, et al. Among authors: shukla n. Pediatr Blood Cancer. 2016 Aug;63(8):1368-74. doi: 10.1002/pbc.26002. Epub 2016 Apr 15. Pediatr Blood Cancer. 2016. PMID: 27082517 Free PMC article.

10

Proteasome Addiction Defined in Ewing Sarcoma Is Effectively Targeted by a Novel Class of 19S Proteasome Inhibitors.

Shukla N, Somwar R, Smith RS, Ambati S, Munoz S, Merchant M, D'Arcy P, Wang X, Kobos R, Antczak C, Bhinder B, Shum D, Radu C, Yang G, Taylor BS, Ng CK, Weigelt B, Khodos I, de Stanchina E, Reis-Filho JS, Ouerfelli O, Linder S, Djaballah H, Ladanyi M. Shukla N, et al. Cancer Res. 2016 Aug 1;76(15):4525-34. doi: 10.1158/0008-5472.CAN-16-1040. Epub 2016 Jun 2. Cancer Res. 2016. PMID: 27256563 Free PMC article.

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