Anderson RF - Search Results

1

Molecular and cellular pharmacology of the hypoxia-activated prodrug TH-302.

Meng F, Evans JW, Bhupathi D, Banica M, Lan L, Lorente G, Duan JX, Cai X, Mowday AM, Guise CP, Maroz A, Anderson RF, Patterson AV, Stachelek GC, Glazer PM, Matteucci MD, Hart CP. Meng F, et al. Among authors: anderson rf. Mol Cancer Ther. 2012 Mar;11(3):740-51. doi: 10.1158/1535-7163.MCT-11-0634. Epub 2011 Dec 6. Mol Cancer Ther. 2012. PMID: 22147748

2

Structure-activity relationships of 1,2,4-benzotriazine 1,4-dioxides as hypoxia-selective analogues of tirapazamine.

Hay MP, Gamage SA, Kovacs MS, Pruijn FB, Anderson RF, Patterson AV, Wilson WR, Brown JM, Denny WA. Hay MP, et al. Among authors: anderson rf. J Med Chem. 2003 Jan 2;46(1):169-82. doi: 10.1021/jm020367+. J Med Chem. 2003. PMID: 12502371

3

Cytosine-gated hole creation and transfer in DNA in aqueous solution.

Anderson RF, Shinde SS, Maroz A. Anderson RF, et al. J Am Chem Soc. 2006 Dec 20;128(50):15966-7. doi: 10.1021/ja0658416. J Am Chem Soc. 2006. PMID: 17165712

4

Reactivity of ubiquinone and ubiquinol with superoxide and the hydroperoxyl radical: implications for in vivo antioxidant activity.

Maroz A, Anderson RF, Smith RA, Murphy MP. Maroz A, et al. Among authors: anderson rf. Free Radic Biol Med. 2009 Jan 1;46(1):105-9. doi: 10.1016/j.freeradbiomed.2008.09.033. Epub 2008 Oct 14. Free Radic Biol Med. 2009. PMID: 18977291

5

One-electron reduction potential of the neutral guanyl radical in the GC base pair of duplex DNA.

Shinde SS, Maroz A, Hay MP, Anderson RF. Shinde SS, et al. Among authors: anderson rf. J Am Chem Soc. 2009 Apr 15;131(14):5203-7. doi: 10.1021/ja8087339. J Am Chem Soc. 2009. PMID: 19320486 Free PMC article.

6

Spin trapping of radicals other than the *OH radical upon reduction of the anticancer agent tirapazamine by cytochrome P450 reductase.

Shinde SS, Hay MP, Patterson AV, Denny WA, Anderson RF. Shinde SS, et al. Among authors: anderson rf. J Am Chem Soc. 2009 Oct 14;131(40):14220-1. doi: 10.1021/ja906860a. J Am Chem Soc. 2009. PMID: 19772319

7

Characterization of radicals formed following enzymatic reduction of 3-substituted analogues of the hypoxia-selective cytotoxin 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine).

Shinde SS, Maroz A, Hay MP, Patterson AV, Denny WA, Anderson RF. Shinde SS, et al. Among authors: anderson rf. J Am Chem Soc. 2010 Mar 3;132(8):2591-9. doi: 10.1021/ja908689f. J Am Chem Soc. 2010. PMID: 20141134

8

Characterisation of radicals formed by the triazine 1,4-dioxide hypoxia-activated prodrug, SN30000.

Anderson RF, Yadav P, Patel D, Reynisson J, Tipparaju SR, Guise CP, Patterson AV, Denny WA, Maroz A, Shinde SS, Hay MP. Anderson RF, et al. Org Biomol Chem. 2014 Jun 7;12(21):3386-92. doi: 10.1039/c4ob00236a. Epub 2014 Apr 16. Org Biomol Chem. 2014. PMID: 24737463

9

Rational design of an AKR1C3-resistant analog of PR-104 for enzyme-prodrug therapy.

Mowday AM, Ashoorzadeh A, Williams EM, Copp JN, Silva S, Bull MR, Abbattista MR, Anderson RF, Flanagan JU, Guise CP, Ackerley DF, Smaill JB, Patterson AV. Mowday AM, et al. Among authors: anderson rf. Biochem Pharmacol. 2016 Sep 15;116:176-87. doi: 10.1016/j.bcp.2016.07.015. Epub 2016 Jul 22. Biochem Pharmacol. 2016. PMID: 27453434

10

Prototyping kinase inhibitor-cytotoxin anticancer mutual prodrugs activated by tumour hypoxia: A chemical proof of concept study.

Sansom GN, Kirk NS, Guise CP, Anderson RF, Smaill JB, Patterson AV, Kelso MJ. Sansom GN, et al. Among authors: anderson rf. Bioorg Med Chem Lett. 2019 May 15;29(10):1215-1219. doi: 10.1016/j.bmcl.2019.03.015. Epub 2019 Mar 13. Bioorg Med Chem Lett. 2019. PMID: 30885680

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