López-Guerra M - Search Results

1

A new genetic abnormality leading to TP53 gene deletion in chronic lymphocytic leukaemia.

López C, Baumann T, Costa D, López-Guerra M, Navarro A, Gómez C, Arias A, Muñoz C, Rozman M, Villamor N, Colomer D, Montserrat E, Campo E, Carrió A. López C, et al. Br J Haematol. 2012 Mar;156(5):612-8. doi: 10.1111/j.1365-2141.2011.08978.x. Epub 2011 Dec 9. Br J Haematol. 2012. PMID: 22150335 Free article.

2

Selective inhibition of IkappaB kinase sensitizes mantle cell lymphoma B cells to TRAIL by decreasing cellular FLIP level.

Roué G, Pérez-Galán P, López-Guerra M, Villamor N, Campo E, Colomer D. Roué G, et al. J Immunol. 2007 Feb 1;178(3):1923-30. doi: 10.4049/jimmunol.178.3.1923. J Immunol. 2007. PMID: 17237443

3

BCL-2 phosphorylation modulates sensitivity to the BH3 mimetic GX15-070 (Obatoclax) and reduces its synergistic interaction with bortezomib in chronic lymphocytic leukemia cells.

Pérez-Galán P, Roué G, López-Guerra M, Nguyen M, Villamor N, Montserrat E, Shore GC, Campo E, Colomer D. Pérez-Galán P, et al. Leukemia. 2008 Sep;22(9):1712-20. doi: 10.1038/leu.2008.175. Epub 2008 Jul 3. Leukemia. 2008. PMID: 18596739

4

Identification of TIGAR in the equilibrative nucleoside transporter 2-mediated response to fludarabine in chronic lymphocytic leukemia cells.

López-Guerra M, Trigueros-Motos L, Molina-Arcas M, Villamor N, Casado FJ, Montserrat E, Campo E, Colomer D, Pastor-Anglada M. López-Guerra M, et al. Haematologica. 2008 Dec;93(12):1843-51. doi: 10.3324/haematol.13186. Epub 2008 Oct 22. Haematologica. 2008. PMID: 18945750 Free article.

5

Bendamustine is effective in p53-deficient B-cell neoplasms and requires oxidative stress and caspase-independent signaling.

Roué G, López-Guerra M, Milpied P, Pérez-Galán P, Villamor N, Montserrat E, Campo E, Colomer D. Roué G, et al. Clin Cancer Res. 2008 Nov 1;14(21):6907-15. doi: 10.1158/1078-0432.CCR-08-0388. Clin Cancer Res. 2008. PMID: 18980985

6

p65 activity and ZAP-70 status predict the sensitivity of chronic lymphocytic leukemia cells to the selective IkappaB kinase inhibitor BMS-345541.

López-Guerra M, Roué G, Pérez-Galán P, Alonso R, Villamor N, Montserrat E, Campo E, Colomer D. López-Guerra M, et al. Clin Cancer Res. 2009 Apr 15;15(8):2767-76. doi: 10.1158/1078-0432.CCR-08-2382. Epub 2009 Apr 7. Clin Cancer Res. 2009. PMID: 19351760

7

Forodesine has high antitumor activity in chronic lymphocytic leukemia and activates p53-independent mitochondrial apoptosis by induction of p73 and BIM.

Alonso R, López-Guerra M, Upshaw R, Bantia S, Smal C, Bontemps F, Manz C, Mehrling T, Villamor N, Campo E, Montserrat E, Colomer D. Alonso R, et al. Blood. 2009 Aug 20;114(8):1563-75. doi: 10.1182/blood-2009-02-207654. Epub 2009 Jun 18. Blood. 2009. PMID: 19541822 Free article.

8

NF-kappaB as a therapeutic target in chronic lymphocytic leukemia.

Lopez-Guerra M, Colomer D. Lopez-Guerra M, et al. Expert Opin Ther Targets. 2010 Mar;14(3):275-88. doi: 10.1517/14728221003598930. Expert Opin Ther Targets. 2010. PMID: 20148715 Review.

9

Cell death targeting therapies in B lymphoid malignancies.

Saborit-Villarroya I, Roué G, López-Guerra M, Alonso R, Xargay-Torrent S, Rosich L, Colomer D. Saborit-Villarroya I, et al. Curr Drug Targets. 2010 Jul;11(7):769-80. doi: 10.2174/138945010791320863. Curr Drug Targets. 2010. PMID: 20370650 Review.

10

The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78.

Roué G, Pérez-Galán P, Mozos A, López-Guerra M, Xargay-Torrent S, Rosich L, Saborit-Villarroya I, Normant E, Campo E, Colomer D. Roué G, et al. Blood. 2011 Jan 27;117(4):1270-9. doi: 10.1182/blood-2010-04-278853. Epub 2010 Nov 24. Blood. 2011. PMID: 21106982 Free article.

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