Ellis-Grosse EJ - Search Results

1

Frequentist and Bayesian pharmacometric-based approaches to facilitate critically needed new antibiotic development: overcoming lies, damn lies, and statistics.

Ambrose PG, Hammel JP, Bhavnani SM, Rubino CM, Ellis-Grosse EJ, Drusano GL. Ambrose PG, et al. Antimicrob Agents Chemother. 2012 Mar;56(3):1466-70. doi: 10.1128/AAC.01743-10. Epub 2011 Dec 12. Antimicrob Agents Chemother. 2012. PMID: 22155834 Free PMC article. Clinical Trial.

2

Application of patient population-derived pharmacokinetic-pharmacodynamic relationships to tigecycline breakpoint determination for staphylococci and streptococci.

Ambrose PG, Meagher AK, Passarell JA, Van Wart SA, Cirincione BB, Bhavnani SM, Ellis-Grosse E. Ambrose PG, et al. Diagn Microbiol Infect Dis. 2009 Feb;63(2):155-9. doi: 10.1016/j.diagmicrobio.2008.10.011. Diagn Microbiol Infect Dis. 2009. PMID: 19150707

3

In Vivo Pharmacokinetics and Pharmacodynamics of ZTI-01 (Fosfomycin for Injection) in the Neutropenic Murine Thigh Infection Model against Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa.

Lepak AJ, Zhao M, VanScoy B, Taylor DS, Ellis-Grosse E, Ambrose PG, Andes DR. Lepak AJ, et al. Antimicrob Agents Chemother. 2017 May 24;61(6):e00476-17. doi: 10.1128/AAC.00476-17. Print 2017 Jun. Antimicrob Agents Chemother. 2017. PMID: 28396549 Free PMC article.

4

Evaluation of tigecycline penetration into colon wall tissue and epithelial lining fluid using a population pharmacokinetic model and Monte Carlo simulation.

Rubino CM, Ma L, Bhavnani SM, Korth-Bradley J, Speth J, Ellis-Grosse E, Rodvold KR, Ambrose PG, Drusano GL. Rubino CM, et al. Antimicrob Agents Chemother. 2007 Nov;51(11):4085-9. doi: 10.1128/AAC.00065-07. Epub 2007 Sep 10. Antimicrob Agents Chemother. 2007. PMID: 17846139 Free PMC article. Clinical Trial.

5

Pharmacokinetic-pharmacodynamic considerations in the design of hospital-acquired or ventilator-associated bacterial pneumonia studies: look before you leap!

Ambrose PG, Bhavnani SM, Ellis-Grosse EJ, Drusano GL. Ambrose PG, et al. Clin Infect Dis. 2010 Aug 1;51 Suppl 1:S103-10. doi: 10.1086/653057. Clin Infect Dis. 2010. PMID: 20597657 Review.

6

Exploration of the Pharmacokinetic-Pharmacodynamic Relationships for Fosfomycin Efficacy Using an In Vitro Infection Model.

VanScoy BD, McCauley J, Ellis-Grosse EJ, Okusanya OO, Bhavnani SM, Forrest A, Ambrose PG. VanScoy BD, et al. Antimicrob Agents Chemother. 2015 Dec;59(12):7170-7. doi: 10.1128/AAC.04955-14. Epub 2015 Jun 22. Antimicrob Agents Chemother. 2015. PMID: 26100706 Free PMC article.

7

Relationship between Fosfomycin Exposure and Amplification of Escherichia coli Subpopulations with Reduced Susceptibility in a Hollow-Fiber Infection Model.

VanScoy B, McCauley J, Bhavnani SM, Ellis-Grosse EJ, Ambrose PG. VanScoy B, et al. Among authors: ellis grosse ej. Antimicrob Agents Chemother. 2016 Aug 22;60(9):5141-5. doi: 10.1128/AAC.00355-16. Print 2016 Sep. Antimicrob Agents Chemother. 2016. PMID: 27270274 Free PMC article.

8

New EMA guideline for antimicrobial development.

Ambrose PG, Bhavnani SM, Dudley MN, Ellis-Grosse E, Rubino CM, Drusano GL. Ambrose PG, et al. Lancet Infect Dis. 2012 Apr;12(4):265-6. doi: 10.1016/S1473-3099(12)70046-4. Lancet Infect Dis. 2012. PMID: 22459079 No abstract available.

9

Use of a clinically derived exposure-response relationship to evaluate potential tigecycline-Enterobacteriaceae susceptibility breakpoints.

Ambrose PG, Meagher AK, Passarell JA, Van Wart SA, Cirincione BB, Rubino CM, Korth-Bradley JM, Babinchak T, Ellis-Grosse E. Ambrose PG, et al. Diagn Microbiol Infect Dis. 2009 Jan;63(1):38-42. doi: 10.1016/j.diagmicrobio.2008.09.014. Diagn Microbiol Infect Dis. 2009. PMID: 19073300

10

The pharmacokinetic and pharmacodynamic profile of tigecycline.

Meagher AK, Ambrose PG, Grasela TH, Ellis-Grosse EJ. Meagher AK, et al. Clin Infect Dis. 2005 Sep 1;41 Suppl 5:S333-40. doi: 10.1086/431674. Clin Infect Dis. 2005. PMID: 16080071 Review.

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