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Page 1
Clinical manufacturing of recombinant human interleukin 15. I. Production cell line development and protein expression in E. coli with stop codon optimization.
Vyas VV, Esposito D, Sumpter TL, Broadt TL, Hartley J, Knapp GC 4th, Cheng W, Jiang MS, Roach JM, Yang X, Giardina SL, Mitra G, Yovandich JL, Creekmore SP, Waldmann TA, Zhu J. Vyas VV, et al. Among authors: mitra g. Biotechnol Prog. 2012 Mar-Apr;28(2):497-507. doi: 10.1002/btpr.746. Epub 2011 Dec 9. Biotechnol Prog. 2012. PMID: 22162520 Free PMC article.
Characterization of recombinant human IL-15 deamidation and its practical elimination through substitution of asparagine 77.
Nellis DF, Michiel DF, Jiang MS, Esposito D, Davis R, Jiang H, Korrell A, Knapp GC 4th, Lucernoni LE, Nelson RE, Pritt EM, Procter LV, Rogers M, Sumpter TL, Vyas VV, Waybright TJ, Yang X, Zheng AM, Yovandich JL, Gilly JA, Mitra G, Zhu J. Nellis DF, et al. Among authors: mitra g. Pharm Res. 2012 Mar;29(3):722-38. doi: 10.1007/s11095-011-0597-0. Epub 2011 Oct 19. Pharm Res. 2012. PMID: 22009587
Mammalian cell transient expression, non-affinity purification, and characterization of human recombinant IGFBP7, an IGF-1 targeting therapeutic protein.
Jiang MS, Yang X, Esposito D, Nelson E, Yuan J, Hopkins RF, Broadt T, Xiao Z, Colantonio S, Prieto DA, Welch AR, Creekmore SP, Mitra G, Zhu J. Jiang MS, et al. Among authors: mitra g. Int Immunopharmacol. 2015 Dec;29(2):476-487. doi: 10.1016/j.intimp.2015.10.008. Epub 2015 Oct 23. Int Immunopharmacol. 2015. PMID: 26474694
MTS dye based colorimetric CTLL-2 cell proliferation assay for product release and stability monitoring of interleukin-15: assay qualification, standardization and statistical analysis.
Soman G, Yang X, Jiang H, Giardina S, Vyas V, Mitra G, Yovandich J, Creekmore SP, Waldmann TA, Quiñones O, Alvord WG. Soman G, et al. Among authors: mitra g. J Immunol Methods. 2009 Aug 31;348(1-2):83-94. doi: 10.1016/j.jim.2009.07.010. Epub 2009 Jul 30. J Immunol Methods. 2009. PMID: 19646987 Free PMC article.
165 results