Lundgren K - Search Results

1

Comparative analysis of novel and conventional Hsp90 inhibitors on HIF activity and angiogenic potential in clear cell renal cell carcinoma: implications for clinical evaluation.

Bohonowych JE, Peng S, Gopal U, Hance MW, Wing SB, Argraves KM, Lundgren K, Isaacs JS. Bohonowych JE, et al. Among authors: lundgren k. BMC Cancer. 2011 Dec 15;11:520. doi: 10.1186/1471-2407-11-520. BMC Cancer. 2011. PMID: 22172030 Free PMC article.

2

BIIB021, a novel Hsp90 inhibitor, sensitizes head and neck squamous cell carcinoma to radiotherapy.

Yin X, Zhang H, Lundgren K, Wilson L, Burrows F, Shores CG. Yin X, et al. Among authors: lundgren k. Int J Cancer. 2010 Mar 1;126(5):1216-25. doi: 10.1002/ijc.24815. Int J Cancer. 2010. PMID: 19662650

3

Identification of new biomarkers for clinical trials of Hsp90 inhibitors.

Zhang H, Chung D, Yang YC, Neely L, Tsurumoto S, Fan J, Zhang L, Biamonte M, Brekken J, Lundgren K, Burrows F. Zhang H, et al. Among authors: lundgren k. Mol Cancer Ther. 2006 May;5(5):1256-64. doi: 10.1158/1535-7163.MCT-05-0537. Mol Cancer Ther. 2006. PMID: 16731758

4

The topoisomerase II-Hsp90 complex: a new chemotherapeutic target?

Barker CR, Hamlett J, Pennington SR, Burrows F, Lundgren K, Lough R, Watson AJ, Jenkins JR. Barker CR, et al. Among authors: lundgren k. Int J Cancer. 2006 Jun 1;118(11):2685-93. doi: 10.1002/ijc.21717. Int J Cancer. 2006. PMID: 16385570

5

BIIB021, a synthetic Hsp90 inhibitor, has broad application against tumors with acquired multidrug resistance.

Zhang H, Neely L, Lundgren K, Yang YC, Lough R, Timple N, Burrows F. Zhang H, et al. Among authors: lundgren k. Int J Cancer. 2010 Mar 1;126(5):1226-34. doi: 10.1002/ijc.24825. Int J Cancer. 2010. PMID: 19676042

6

BIIB021, an orally available, fully synthetic small-molecule inhibitor of the heat shock protein Hsp90.

Lundgren K, Zhang H, Brekken J, Huser N, Powell RE, Timple N, Busch DJ, Neely L, Sensintaffar JL, Yang YC, McKenzie A, Friedman J, Scannevin R, Kamal A, Hong K, Kasibhatla SR, Boehm MF, Burrows FJ. Lundgren K, et al. Mol Cancer Ther. 2009 Apr;8(4):921-9. doi: 10.1158/1535-7163.MCT-08-0758. Mol Cancer Ther. 2009. PMID: 19372565

7

Oncogenic MST1R activity in pancreatic and gastric cancer represents a valid target of HSP90 inhibitors.

Moser C, Lang SA, Hackl C, Zhang H, Lundgren K, Hong V, McKenzie A, Weber B, Park JS, Schlitt HJ, Geissler EK, Jung YD, Stoeltzing O. Moser C, et al. Among authors: lundgren k. Anticancer Res. 2012 Feb;32(2):427-37. Anticancer Res. 2012. PMID: 22287729

8

An investigation into the potential use of serum Hsp70 as a novel tumour biomarker for Hsp90 inhibitors.

Dakappagari N, Neely L, Tangri S, Lundgren K, Hipolito L, Estrellado A, Burrows F, Zhang H. Dakappagari N, et al. Among authors: lundgren k. Biomarkers. 2010 Feb;15(1):31-8. doi: 10.3109/13547500903261347. Biomarkers. 2010. PMID: 19747088

9

Heat shock protein 90 inhibitor BIIB021 (CNF2024) depletes NF-kappaB and sensitizes Hodgkin's lymphoma cells for natural killer cell-mediated cytotoxicity.

Böll B, Eltaib F, Reiners KS, von Tresckow B, Tawadros S, Simhadri VR, Burrows FJ, Lundgren K, Hansen HP, Engert A, von Strandmann EP. Böll B, et al. Among authors: lundgren k. Clin Cancer Res. 2009 Aug 15;15(16):5108-16. doi: 10.1158/1078-0432.CCR-09-0213. Epub 2009 Aug 11. Clin Cancer Res. 2009. PMID: 19671844

10

EC144, a synthetic inhibitor of heat shock protein 90, blocks innate and adaptive immune responses in models of inflammation and autoimmunity.

Yun TJ, Harning EK, Giza K, Rabah D, Li P, Arndt JW, Luchetti D, Biamonte MA, Shi J, Lundgren K, Manning A, Kehry MR. Yun TJ, et al. Among authors: lundgren k. J Immunol. 2011 Jan 1;186(1):563-75. doi: 10.4049/jimmunol.1000222. Epub 2010 Dec 3. J Immunol. 2011. PMID: 21131419

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