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Development of covalent chemogenetic K2P channel activators.
Deal PE, Lee H, Mondal A, Lolicato M, Mendonça PRF, Black H, Jang S, El-Hilali X, Bryant C, Isacoff EY, Renslo AR, Minor DL Jr. Deal PE, et al. Among authors: minor dl jr. Cell Chem Biol. 2024 Jul 18;31(7):1305-1323.e9. doi: 10.1016/j.chembiol.2024.06.006. Cell Chem Biol. 2024. PMID: 39029456
Development of covalent chemogenetic K2P channel activators.
Deal PE, Lee H, Mondal A, Lolicato M, de Mendonca PRF, Black H, El-Hilali X, Bryant C, Isacoff EY, Renslo AR, Minor DL Jr. Deal PE, et al. Among authors: minor dl jr. bioRxiv [Preprint]. 2023 Oct 18:2023.10.15.561774. doi: 10.1101/2023.10.15.561774. bioRxiv. 2023. Update in: Cell Chem Biol. 2024 Jul 18;31(7):1305-1323.e9. doi: 10.1016/j.chembiol.2024.06.006 PMID: 37905049 Free PMC article. Updated. Preprint.
EMC chaperone-CaV structure reveals an ion channel assembly intermediate.
Chen Z, Mondal A, Abderemane-Ali F, Jang S, Niranjan S, Montaño JL, Zaro BW, Minor DL Jr. Chen Z, et al. Among authors: minor dl jr. Nature. 2023 Jul;619(7969):410-419. doi: 10.1038/s41586-023-06175-5. Epub 2023 May 17. Nature. 2023. PMID: 37196677 Free PMC article.
Structural basis for CaVα2δ:gabapentin binding.
Chen Z, Mondal A, Minor DL Jr. Chen Z, et al. Among authors: minor dl jr. Nat Struct Mol Biol. 2023 Jun;30(6):735-739. doi: 10.1038/s41594-023-00951-7. Epub 2023 Mar 27. Nat Struct Mol Biol. 2023. PMID: 36973510 Free PMC article.
Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Arrigoni C, Lolicato M, Shaya D, Rohaim A, Findeisen F, Fong LK, Colleran CM, Dominik P, Kim SS, Schuermann JP, DeGrado WF, Grabe M, Kossiakoff AA, Minor DL Jr. Arrigoni C, et al. Among authors: minor dl jr. Nat Struct Mol Biol. 2022 Jun;29(6):537-548. doi: 10.1038/s41594-022-00775-x. Epub 2022 Jun 2. Nat Struct Mol Biol. 2022. PMID: 35655098 Free PMC article.
The Polysite Pharmacology of TREK K2P Channels.
Pope L, Minor DL Jr. Pope L, et al. Among authors: minor dl jr. Adv Exp Med Biol. 2021;1349:51-65. doi: 10.1007/978-981-16-4254-8_4. Adv Exp Med Biol. 2021. PMID: 35138610 Free PMC article.
85 results