Houghton PJ - Search Results

1

Potent inhibition of angiogenesis by the IGF-1 receptor-targeting antibody SCH717454 is reversed by IGF-2.

Bid HK, Zhan J, Phelps DA, Kurmasheva RT, Houghton PJ. Bid HK, et al. Among authors: houghton pj. Mol Cancer Ther. 2012 Mar;11(3):649-59. doi: 10.1158/1535-7163.MCT-11-0575. Epub 2011 Dec 21. Mol Cancer Ther. 2012. PMID: 22188815 Free PMC article.

2

Developing new agents for the treatment of childhood cancer.

Kurmasheva R, Morton C, Houghton PJ. Kurmasheva R, et al. Among authors: houghton pj. Curr Opin Investig Drugs. 2005 Dec;6(12):1215-27. Curr Opin Investig Drugs. 2005. PMID: 16372407 Review.

3

IRS-1: auditing the effectiveness of mTOR inhibitors.

Easton JB, Kurmasheva RT, Houghton PJ. Easton JB, et al. Among authors: houghton pj. Cancer Cell. 2006 Mar;9(3):153-5. doi: 10.1016/j.ccr.2006.02.027. Cancer Cell. 2006. PMID: 16530700 Free article. Review.

4

Pharmacologic inhibition of cyclin-dependent kinase 4/6 activity arrests proliferation in myoblasts and rhabdomyosarcoma-derived cells.

Saab R, Bills JL, Miceli AP, Anderson CM, Khoury JD, Fry DW, Navid F, Houghton PJ, Skapek SX. Saab R, et al. Among authors: houghton pj. Mol Cancer Ther. 2006 May;5(5):1299-308. doi: 10.1158/1535-7163.MCT-05-0383. Mol Cancer Ther. 2006. PMID: 16731763

5

IGF-I mediated survival pathways in normal and malignant cells.

Kurmasheva RT, Houghton PJ. Kurmasheva RT, et al. Among authors: houghton pj. Biochim Biophys Acta. 2006 Aug;1766(1):1-22. doi: 10.1016/j.bbcan.2006.05.003. Epub 2006 Jun 7. Biochim Biophys Acta. 2006. PMID: 16844299 Review.

6

Predicted mechanisms of resistance to mTOR inhibitors.

Kurmasheva RT, Huang S, Houghton PJ. Kurmasheva RT, et al. Among authors: houghton pj. Br J Cancer. 2006 Oct 23;95(8):955-60. doi: 10.1038/sj.bjc.6603353. Epub 2006 Sep 5. Br J Cancer. 2006. PMID: 16953237 Free PMC article. Review.

7

SK-NEP-1 and Rh1 are Ewing family tumor lines.

Smith MA, Morton CL, Phelps D, Girtman K, Neale G, Houghton PJ. Smith MA, et al. Among authors: houghton pj. Pediatr Blood Cancer. 2008 Mar;50(3):703-6. doi: 10.1002/pbc.21099. Pediatr Blood Cancer. 2008. PMID: 17154184

8

Negative regulation of ASK1 by p21Cip1 involves a small domain that includes Serine 98 that is phosphorylated by ASK1 in vivo.

Zhan J, Easton JB, Huang S, Mishra A, Xiao L, Lacy ER, Kriwacki RW, Houghton PJ. Zhan J, et al. Among authors: houghton pj. Mol Cell Biol. 2007 May;27(9):3530-41. doi: 10.1128/MCB.00086-06. Epub 2007 Feb 26. Mol Cell Biol. 2007. PMID: 17325029 Free PMC article.

9

Differential regulation of vascular endothelial growth factor by Akt and mammalian target of rapamycin inhibitors in cell lines derived from childhood solid tumors.

Kurmasheva RT, Harwood FC, Houghton PJ. Kurmasheva RT, et al. Among authors: houghton pj. Mol Cancer Ther. 2007 May;6(5):1620-8. doi: 10.1158/1535-7163.MCT-06-0646. Epub 2007 May 4. Mol Cancer Ther. 2007. PMID: 17483438

10

Pediatric oncology.

Kurmasheva RT, Houghton PJ. Kurmasheva RT, et al. Among authors: houghton pj. Curr Opin Chem Biol. 2007 Aug;11(4):424-32. doi: 10.1016/j.cbpa.2007.05.037. Epub 2007 Jul 24. Curr Opin Chem Biol. 2007. PMID: 17652007 Free PMC article. Review.

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