Carocci A - Search Results

1

Synthesis and toxicopharmacological evaluation of m-hydroxymexiletine, the first metabolite of mexiletine more potent than the parent compound on voltage-gated sodium channels.

Catalano A, Desaphy JF, Lentini G, Carocci A, Di Mola A, Bruno C, Carbonara R, De Palma A, Budriesi R, Ghelardini C, Perrone MG, Colabufo NA, Conte Camerino D, Franchini C. Catalano A, et al. Among authors: carocci a. J Med Chem. 2012 Feb 9;55(3):1418-22. doi: 10.1021/jm201197z. Epub 2012 Jan 31. J Med Chem. 2012. PMID: 22191686

2

Facile entry to (-)-(R)- and (+)-(S)-mexiletine.

Carocci A, Franchini C, Lentini G, Loiodice F, Tortorella V. Carocci A, et al. Chirality. 2000 Mar;12(3):103-6. doi: 10.1002/(SICI)1520-636X(2000)12:3<103::AID-CHIR1>3.0.CO;2-X. Chirality. 2000. PMID: 10689287

3

Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na(+) channels.

Franchini C, Carocci A, Catalano A, Cavalluzzi MM, Corbo F, Lentini G, Scilimati A, Tortorella P, Camerino DC, De Luca A. Franchini C, et al. Among authors: carocci a. J Med Chem. 2003 Nov 20;46(24):5238-48. doi: 10.1021/jm030865y. J Med Chem. 2003. PMID: 14613326

4

Stereospecific synthesis of "para-hydroxymexiletine" and sodium channel blocking activity evaluation.

Catalano A, Carocci A, Fracchiolla G, Franchini C, Lentini G, Tortorella V, De Luca A, De Bellis M, Desaphy JF, Conte Camerino D. Catalano A, et al. Among authors: carocci a. Chirality. 2004 Feb;16(2):72-8. doi: 10.1002/chir.10307. Chirality. 2004. PMID: 14712469

5

Facile, alternative route to lubeluzole, its enantiomer, and the racemate.

Bruno C, Carocci A, Catalano A, Cavalluzzi MM, Corbo F, Franchini C, Lentini G, Tortorella V. Bruno C, et al. Among authors: carocci a. Chirality. 2006 May 5;18(4):227-31. doi: 10.1002/chir.20240. Chirality. 2006. PMID: 16521088

6

AT1 receptor ligands: virtual-screening-based design with TOPP descriptors, synthesis, and biological evaluation of pyrrolidine derivatives.

Lamanna C, Catalano A, Carocci A, Di Mola A, Franchini C, Tortorella V, Vanderheyden PM, Sinicropi MS, Watson KA, Sciabola S. Lamanna C, et al. Among authors: carocci a. ChemMedChem. 2007 Sep;2(9):1298-310. doi: 10.1002/cmdc.200700082. ChemMedChem. 2007. PMID: 17628868

7

Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents.

Catalano A, Carocci A, Corbo F, Franchini C, Muraglia M, Scilimati A, De Bellis M, De Luca A, Camerino DC, Sinicropi MS, Tortorella V. Catalano A, et al. Among authors: carocci a. Eur J Med Chem. 2008 Nov;43(11):2535-40. doi: 10.1016/j.ejmech.2008.01.023. Epub 2008 Jan 31. Eur J Med Chem. 2008. PMID: 18342401

8

Synthesis and in vitro sodium channel blocking activity evaluation of novel homochiral mexiletine analogs.

Carocci A, Catalano A, Bruno C, Lentini G, Franchini C, De Bellis M, De Luca A, Conte Camerino D. Carocci A, et al. Chirality. 2010 Mar;22(3):299-307. doi: 10.1002/chir.20741. Chirality. 2010. PMID: 19544349

9

Chiral aryloxyalkylamines: Selective 5-HT(1B/1D) activation and analgesic activity.

Carocci A, Lentini G, Catalano A, Cavalluzzi MM, Bruno C, Muraglia M, Colabufo NA, Galeotti N, Corbo F, Matucci R, Ghelardini C, Franchini C. Carocci A, et al. ChemMedChem. 2010 May 3;5(5):696-704. doi: 10.1002/cmdc.200900530. ChemMedChem. 2010. PMID: 20235265

10

Hydroxylated analogs of mexiletine as tools for structural-requirements investigation of the sodium channel blocking activity.

Catalano A, Carocci A, Cavalluzzi MM, Di Mola A, Lentini G, Lovece A, Dipalma A, Costanza T, Desaphy JF, Conte Camerino D, Franchini C. Catalano A, et al. Among authors: carocci a. Arch Pharm (Weinheim). 2010 Jun;343(6):325-32. doi: 10.1002/ardp.200900218. Arch Pharm (Weinheim). 2010. PMID: 20509146

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