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Steroidal C-21 heteroaryl thioethers (Part 2): discovery of orally bioavailable selective glucocorticoid receptor modulators (dissociated steroids).
Biju P, McCormick K, Aslanian R, Berlin M, Solomon D, Wang H, Lee YJ, Bitar R, Prelusky D, McLeod R, Jia Y, Fernandez X, Eckel S, House A, Lieber G, Jimenez J, Kelly G, Chapman R, Phillips J, Anthes J. Biju P, et al. Among authors: kelly g. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1086-90. doi: 10.1016/j.bmcl.2011.11.120. Epub 2011 Dec 7. Bioorg Med Chem Lett. 2012. PMID: 22197391
Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients.
Pickering H, Schaenman J, Phan HV, Maguire C, Tsitsiklis A, Rouphael N, Higuita NIA, Atkinson MA, Brakenridge S, Fung M, Messer W; IMPACC Network; Salehi-Rad R, Altman MC, Becker PM, Bosinger SE, Eckalbar W, Hoch A, Doni Jayavelu N, Kim-Schulze S, Jenkins M, Kleinstein SH, Krammer F, Maecker HT, Ozonoff A, Diray-Arce J, Shaw A, Baden L, Levy O, Reed EF, Langelier CR. Pickering H, et al. Nat Commun. 2025 Jan 10;16(1):586. doi: 10.1038/s41467-025-55823-z. Nat Commun. 2025. PMID: 39794319 Free PMC article.
A 2OGD multi-gene cluster encompasses functional and tissue specificity that direct furanocoumarin and pyranocoumarin biosynthesis in citrus.
Goldenberg L, Ghuge SA, Doron-Faigenboim A, Carmeli-Weissberg M, Shaya F, Rozen A, Dahan Y, Plesser E, Kelly G, Yaniv Y, Arad T, Ophir R, Sherman A, Carmi N, Eyal Y. Goldenberg L, et al. Among authors: kelly g. New Phytol. 2025 Feb;245(4):1547-1562. doi: 10.1111/nph.20322. Epub 2025 Jan 8. New Phytol. 2025. PMID: 39775733
Context-dependent effects of CDKN2A and other 9p21 gene losses during the evolution of esophageal cancer.
Ganguli P, Basanta CC, Acha-Sagredo A, Misetic H, Armero M, Mendez A, Zahra A, Devonshire G, Kelly G, Freeman A, Green M, Nye E, Bichisecchi A, Bonfanti P; Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium; Rodriguez-Justo M, Spencer J, Fitzgerald RC, Ciccarelli FD. Ganguli P, et al. Among authors: kelly g. Nat Cancer. 2025 Jan 3. doi: 10.1038/s43018-024-00876-0. Online ahead of print. Nat Cancer. 2025. PMID: 39753721
The National Joint Registry Data Quality Audit of elbow arthroplasty.
Hamoodi Z, Shapiro J, Sayers A, Whitehouse MR, Watts AC; NJR DQA-Elbows Collaborators; Abbott J, Abbott S, Adebayo O, Ahmad K, Ahrens P, Akinfala M, Al-Hadithy N, Al-Najjar M, Amirfeyz R, Ankarath S, Ashton F, Aulton K, Auplish S, Austin J, Ayeko S, Azhar R, Bahia R, Baines S, Baldomir M, Barai S, Barkham B, Barrett E, Batten T, Bavan L, Baxter J, Beaumont S, Bentley J, Bhabra G, Bhat M, Bhatt A, Bhingraj M, Bhutta A, Bingham S, Blastland J, Boardman D, Boateng M, Bojarska K, Boksh K, Booker S, Borreshi S, Bould M, Boulton L, Brannan L, Breidaka Z, Brereton R, Brinsden M, Brooker J, Brookes S, Broux C, Brown E, Browne J, Bryant R, Buchanan J, Buck L, Burnett K, Burrows M, Burt J, Burton D, Butt U, Campaner B, Candal-Couto J, Carvell H, Chakravarthy J, Chatterji S, Chaudhury S, Chauhan GS, Chojnowski A, Cittambalam J, Clark D, Gosia Clarke M, Clarke B, Clelland A, Cochrane R, Colbridge K, Cook H, Cooper B, Correa E, Craven J, Crawford J, Curtis S, Cuthbert R, Dainton J, Dale L, Davies S, Davis J, Davis V, Dean B, Dehler T, Dennis S, Der Tavitian J, Desai A, Dhillon SS, Dias R, Dickinson G, Dirckx M, Dixon O, Docker C, Dodenhoff R, Domos P, Draviaraj K, Drew S, Duff C, Duffin S, Dur… See abstract for full author list ➔ Hamoodi Z, et al. Among authors: kelly g. Bone Joint J. 2024 Dec 1;106-B(12):1461-1468. doi: 10.1302/0301-620X.106B12.BJJ-2023-1372.R1. Bone Joint J. 2024. PMID: 39618239
Breathing new insights into the role of mutant p53 in lung cancer.
Chen T, Ashwood LM, Kondrashova O, Strasser A, Kelly G, Sutherland KD. Chen T, et al. Among authors: kelly g. Oncogene. 2025 Feb;44(3):115-129. doi: 10.1038/s41388-024-03219-6. Epub 2024 Nov 20. Oncogene. 2025. PMID: 39567755 Free PMC article. Review.
1,242 results