Chen Y - Search Results

1

Primary amines protect against retinal degeneration in mouse models of retinopathies.

Maeda A, Golczak M, Chen Y, Okano K, Kohno H, Shiose S, Ishikawa K, Harte W, Palczewska G, Maeda T, Palczewski K. Maeda A, et al. Among authors: chen y. Nat Chem Biol. 2011 Dec 25;8(2):170-8. doi: 10.1038/nchembio.759. Nat Chem Biol. 2011. PMID: 22198730 Free PMC article.

2

Noninvasive multiphoton fluorescence microscopy resolves retinol and retinal condensation products in mouse eyes.

Palczewska G, Maeda T, Imanishi Y, Sun W, Chen Y, Williams DR, Piston DW, Maeda A, Palczewski K. Palczewska G, et al. Among authors: chen y. Nat Med. 2010 Dec;16(12):1444-9. doi: 10.1038/nm.2260. Epub 2010 Nov 14. Nat Med. 2010. PMID: 21076393 Free PMC article.

3

Toll-like receptor 3 is required for development of retinopathy caused by impaired all-trans-retinal clearance in mice.

Shiose S, Chen Y, Okano K, Roy S, Kohno H, Tang J, Pearlman E, Maeda T, Palczewski K, Maeda A. Shiose S, et al. Among authors: chen y. J Biol Chem. 2011 Apr 29;286(17):15543-55. doi: 10.1074/jbc.M111.228551. Epub 2011 Mar 7. J Biol Chem. 2011. PMID: 21383019 Free PMC article.

4

Sponge transgenic mouse model reveals important roles for the microRNA-183 (miR-183)/96/182 cluster in postmitotic photoreceptors of the retina.

Zhu Q, Sun W, Okano K, Chen Y, Zhang N, Maeda T, Palczewski K. Zhu Q, et al. Among authors: chen y. J Biol Chem. 2011 Sep 9;286(36):31749-60. doi: 10.1074/jbc.M111.259028. Epub 2011 Jul 15. J Biol Chem. 2011. PMID: 21768104 Free PMC article.

5

Mechanism of all-trans-retinal toxicity with implications for stargardt disease and age-related macular degeneration.

Chen Y, Okano K, Maeda T, Chauhan V, Golczak M, Maeda A, Palczewski K. Chen Y, et al. J Biol Chem. 2012 Feb 10;287(7):5059-69. doi: 10.1074/jbc.M111.315432. Epub 2011 Dec 19. J Biol Chem. 2012. PMID: 22184108 Free PMC article.

6

Retinal cone and rod photoreceptor cells exhibit differential susceptibility to light-induced damage.

Okano K, Maeda A, Chen Y, Chauhan V, Tang J, Palczewska G, Sakai T, Tsuneoka H, Palczewski K, Maeda T. Okano K, et al. Among authors: chen y. J Neurochem. 2012 Apr;121(1):146-56. doi: 10.1111/j.1471-4159.2012.07647.x. Epub 2012 Feb 9. J Neurochem. 2012. PMID: 22220722 Free PMC article.

7

Autophagy protects the retina from light-induced degeneration.

Chen Y, Sawada O, Kohno H, Le YZ, Subauste C, Maeda T, Maeda A. Chen Y, et al. J Biol Chem. 2013 Mar 15;288(11):7506-7518. doi: 10.1074/jbc.M112.439935. Epub 2013 Jan 22. J Biol Chem. 2013. PMID: 23341467 Free PMC article.

8

Photoreceptor proteins initiate microglial activation via Toll-like receptor 4 in retinal degeneration mediated by all-trans-retinal.

Kohno H, Chen Y, Kevany BM, Pearlman E, Miyagi M, Maeda T, Palczewski K, Maeda A. Kohno H, et al. Among authors: chen y. J Biol Chem. 2013 May 24;288(21):15326-41. doi: 10.1074/jbc.M112.448712. Epub 2013 Apr 9. J Biol Chem. 2013. PMID: 23572532 Free PMC article.

9

Systems pharmacology identifies drug targets for Stargardt disease-associated retinal degeneration.

Chen Y, Palczewska G, Mustafi D, Golczak M, Dong Z, Sawada O, Maeda T, Maeda A, Palczewski K. Chen Y, et al. J Clin Invest. 2013 Dec;123(12):5119-34. doi: 10.1172/JCI69076. Epub 2013 Nov 15. J Clin Invest. 2013. PMID: 24231350 Free PMC article.

10

Systems Pharmacology Links GPCRs with Retinal Degenerative Disorders.

Chen Y, Palczewski K. Chen Y, et al. Annu Rev Pharmacol Toxicol. 2016;56:273-98. doi: 10.1146/annurev-pharmtox-010715-103033. Epub 2015 Mar 23. Annu Rev Pharmacol Toxicol. 2016. PMID: 25839098 Free PMC article. Review.

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