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Obesity is associated with hypothalamic injury in rodents and humans.
Thaler JP, Yi CX, Schur EA, Guyenet SJ, Hwang BH, Dietrich MO, Zhao X, Sarruf DA, Izgur V, Maravilla KR, Nguyen HT, Fischer JD, Matsen ME, Wisse BE, Morton GJ, Horvath TL, Baskin DG, Tschöp MH, Schwartz MW. Thaler JP, et al. Among authors: horvath tl. J Clin Invest. 2012 Jan;122(1):153-62. doi: 10.1172/JCI59660. Epub 2011 Dec 27. J Clin Invest. 2012. PMID: 22201683 Free PMC article.
Ghrelin as a potential anti-obesity target.
Horvath TL, Castañeda T, Tang-Christensen M, Pagotto U, Tschöp MH. Horvath TL, et al. Curr Pharm Des. 2003;9(17):1383-95. doi: 10.2174/1381612033454748. Curr Pharm Des. 2003. PMID: 12769730 Review.
Brain circuits regulating energy homeostasis.
Horvath TL, Diano S, Tschöp M. Horvath TL, et al. Neuroscientist. 2004 Jun;10(3):235-46. doi: 10.1177/1073858403262151. Neuroscientist. 2004. PMID: 15155062 Review.
Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity.
Plum L, Ma X, Hampel B, Balthasar N, Coppari R, Münzberg H, Shanabrough M, Burdakov D, Rother E, Janoschek R, Alber J, Belgardt BF, Koch L, Seibler J, Schwenk F, Fekete C, Suzuki A, Mak TW, Krone W, Horvath TL, Ashcroft FM, Brüning JC. Plum L, et al. Among authors: horvath tl. J Clin Invest. 2006 Jul;116(7):1886-901. doi: 10.1172/JCI27123. Epub 2006 Jun 22. J Clin Invest. 2006. PMID: 16794735 Free PMC article.
Diet-induced leptin resistance: the heart of the matter.
Tschöp MH, Hui DY, Horvath TL. Tschöp MH, et al. Among authors: horvath tl. Endocrinology. 2007 Mar;148(3):921-3. doi: 10.1210/en.2006-1708. Endocrinology. 2007. PMID: 17303671 No abstract available.
382 results