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Obesity is associated with hypothalamic injury in rodents and humans.
Thaler JP, Yi CX, Schur EA, Guyenet SJ, Hwang BH, Dietrich MO, Zhao X, Sarruf DA, Izgur V, Maravilla KR, Nguyen HT, Fischer JD, Matsen ME, Wisse BE, Morton GJ, Horvath TL, Baskin DG, Tschöp MH, Schwartz MW. Thaler JP, et al. Among authors: wisse be. J Clin Invest. 2012 Jan;122(1):153-62. doi: 10.1172/JCI59660. Epub 2011 Dec 27. J Clin Invest. 2012. PMID: 22201683 Free PMC article.
Does hypothalamic inflammation cause obesity?
Wisse BE, Schwartz MW. Wisse BE, et al. Cell Metab. 2009 Oct;10(4):241-2. doi: 10.1016/j.cmet.2009.09.003. Cell Metab. 2009. PMID: 19808014 Free article.
Physiology. An integrative view of obesity.
Wisse BE, Kim F, Schwartz MW. Wisse BE, et al. Science. 2007 Nov 9;318(5852):928-9. doi: 10.1126/science.1148032. Science. 2007. PMID: 17991852 No abstract available.
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