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Page 1
Targeting SKCa channels in cancer: potential new therapeutic approaches.
Girault A, Haelters JP, Potier-Cartereau M, Chantôme A, Jaffrés PA, Bougnoux P, Joulin V, Vandier C. Girault A, et al. Among authors: haelters jp. Curr Med Chem. 2012;19(5):697-713. doi: 10.2174/092986712798992039. Curr Med Chem. 2012. PMID: 22204342 Review.
New alkyl-lipid blockers of SK3 channels reduce cancer cell migration and occurrence of metastasis.
Girault A, Haelters JP, Potier-Cartereau M, Chantome A, Pinault M, Marionneau-Lambot S, Oullier T, Simon G, Couthon-Gourvès H, Jaffrès PA, Corbel B, Bougnoux P, Joulin V, Vandier C. Girault A, et al. Among authors: haelters jp. Curr Cancer Drug Targets. 2011 Nov;11(9):1111-25. doi: 10.2174/156800911798073069. Curr Cancer Drug Targets. 2011. PMID: 21999627
Synthetic alkyl-ether-lipid promotes TRPV2 channel trafficking trough PI3K/Akt-girdin axis in cancer cells and increases mammary tumour volume.
Guéguinou M, Felix R, Marionneau-Lambot S, Oullier T, Penna A, Kouba S, Gambade A, Fourbon Y, Ternant D, Arnoult C, Simon G, Bouchet AM, Chantôme A, Harnois T, Haelters JP, Jaffrès PA, Weber G, Bougnoux P, Carreaux F, Mignen O, Vandier C, Potier-Cartereau M. Guéguinou M, et al. Among authors: haelters jp. Cell Calcium. 2021 Jun 12;97:102435. doi: 10.1016/j.ceca.2021.102435. Online ahead of print. Cell Calcium. 2021. PMID: 34167050
New Disaccharide-Based Ether Lipids as SK3 Ion Channel Inhibitors.
Berthe W, Sevrain CM, Chantôme A, Bouchet AM, Gueguinou M, Fourbon Y, Potier-Cartereau M, Haelters JP, Couthon-Gourvès H, Vandier C, Jaffrès PA. Berthe W, et al. Among authors: haelters jp. ChemMedChem. 2016 Jul 19;11(14):1531-9. doi: 10.1002/cmdc.201600147. Epub 2016 Jun 9. ChemMedChem. 2016. PMID: 27278812
SK3/TRPC1/Orai1 complex regulates SOCE-dependent colon cancer cell migration: a novel opportunity to modulate anti-EGFR mAb action by the alkyl-lipid Ohmline.
Guéguinou M, Harnois T, Crottes D, Uguen A, Deliot N, Gambade A, Chantôme A, Haelters JP, Jaffrès PA, Jourdan ML, Weber G, Soriani O, Bougnoux P, Mignen O, Bourmeyster N, Constantin B, Lecomte T, Vandier C, Potier-Cartereau M. Guéguinou M, et al. Among authors: haelters jp. Oncotarget. 2016 Jun 14;7(24):36168-36184. doi: 10.18632/oncotarget.8786. Oncotarget. 2016. PMID: 27102434 Free PMC article.
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