Locke JA - Search Results

1

Allelic loss of the loci containing the androgen synthesis gene, StAR, is prognostic for relapse in intermediate-risk prostate cancer.

Locke JA, Zafarana G, Malloff CA, Lam WL, Sykes J, Pintilie M, Ramnarine VR, Meng A, Ahmed O, Jurisica I, Guns ET, van der Kwast T, Milosevic M, Bristow RG. Locke JA, et al. Prostate. 2012 Sep 1;72(12):1295-305. doi: 10.1002/pros.22478. Epub 2011 Dec 27. Prostate. 2012. PMID: 22213075 Clinical Trial.

2

Copy number alterations of c-MYC and PTEN are prognostic factors for relapse after prostate cancer radiotherapy.

Zafarana G, Ishkanian AS, Malloff CA, Locke JA, Sykes J, Thoms J, Lam WL, Squire JA, Yoshimoto M, Ramnarine VR, Meng A, Ahmed O, Jurisica I, Milosevic M, Pintilie M, van der Kwast T, Bristow RG. Zafarana G, et al. Among authors: locke ja. Cancer. 2012 Aug 15;118(16):4053-62. doi: 10.1002/cncr.26729. Epub 2012 Jan 26. Cancer. 2012. PMID: 22281794 Free article.

3

NKX3.1 haploinsufficiency is prognostic for prostate cancer relapse following surgery or image-guided radiotherapy.

Locke JA, Zafarana G, Ishkanian AS, Milosevic M, Thoms J, Have CL, Malloff CA, Lam WL, Squire JA, Pintilie M, Sykes J, Ramnarine VR, Meng A, Ahmed O, Jurisica I, van der Kwast T, Bristow RG. Locke JA, et al. Clin Cancer Res. 2012 Jan 1;18(1):308-16. doi: 10.1158/1078-0432.CCR-11-2147. Epub 2011 Nov 2. Clin Cancer Res. 2012. PMID: 22048240

4

Synergistic action of image-guided radiotherapy and androgen deprivation therapy.

Locke JA, Dal Pra A, Supiot S, Warde P, Bristow RG. Locke JA, et al. Nat Rev Urol. 2015 Apr;12(4):193-204. doi: 10.1038/nrurol.2015.50. Epub 2015 Mar 24. Nat Rev Urol. 2015. PMID: 25800395 Review.

5

Mechanistic Insights into Molecular Targeting and Combined Modality Therapy for Aggressive, Localized Prostate Cancer.

Dal Pra A, Locke JA, Borst G, Supiot S, Bristow RG. Dal Pra A, et al. Among authors: locke ja. Front Oncol. 2016 Feb 16;6:24. doi: 10.3389/fonc.2016.00024. eCollection 2016. Front Oncol. 2016. PMID: 26909338 Free PMC article. Review.

6

Pomegranate extracts impact the androgen biosynthesis pathways in prostate cancer models in vitro and in vivo.

Ming DS, Pham S, Deb S, Chin MY, Kharmate G, Adomat H, Beheshti EH, Locke J, Guns ET. Ming DS, et al. J Steroid Biochem Mol Biol. 2014 Sep;143:19-28. doi: 10.1016/j.jsbmb.2014.02.006. Epub 2014 Feb 22. J Steroid Biochem Mol Biol. 2014. PMID: 24565566

7

Arachidonic acid activation of intratumoral steroid synthesis during prostate cancer progression to castration resistance.

Locke JA, Guns ES, Lehman ML, Ettinger S, Zoubeidi A, Lubik A, Margiotti K, Fazli L, Adomat H, Wasan KM, Gleave ME, Nelson CC. Locke JA, et al. Prostate. 2010 Feb 15;70(3):239-51. doi: 10.1002/pros.21057. Prostate. 2010. PMID: 19790237

8

A novel communication role for CYP17A1 in the progression of castration-resistant prostate cancer.

Locke JA, Fazli L, Adomat H, Smyl J, Weins K, Lubik AA, Hales DB, Nelson CC, Gleave ME, Tomlinson Guns ES. Locke JA, et al. Prostate. 2009 Jun 15;69(9):928-37. doi: 10.1002/pros.20940. Prostate. 2009. PMID: 19267349

9

Alterations in cholesterol regulation contribute to the production of intratumoral androgens during progression to castration-resistant prostate cancer in a mouse xenograft model.

Leon CG, Locke JA, Adomat HH, Etinger SL, Twiddy AL, Neumann RD, Nelson CC, Guns ES, Wasan KM. Leon CG, et al. Among authors: locke ja. Prostate. 2010 Mar 1;70(4):390-400. doi: 10.1002/pros.21072. Prostate. 2010. PMID: 19866465

10

Dissecting the association between metabolic syndrome and prostate cancer risk: analysis of a large clinical cohort.

Bhindi B, Locke J, Alibhai SMH, Kulkarni GS, Margel DS, Hamilton RJ, Finelli A, Trachtenberg J, Zlotta AR, Toi A, Hersey KM, Evans A, van der Kwast TH, Fleshner NE. Bhindi B, et al. Eur Urol. 2015 Jan;67(1):64-70. doi: 10.1016/j.eururo.2014.01.040. Epub 2014 Feb 14. Eur Urol. 2015. PMID: 24568896

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