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Broadly directed virus-specific CD4+ T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence.
Schulze Zur Wiesch J, Ciuffreda D, Lewis-Ximenez L, Kasprowicz V, Nolan BE, Streeck H, Aneja J, Reyor LL, Allen TM, Lohse AW, McGovern B, Chung RT, Kwok WW, Kim AY, Lauer GM. Schulze Zur Wiesch J, et al. Among authors: kwok ww. J Exp Med. 2012 Jan 16;209(1):61-75. doi: 10.1084/jem.20100388. Epub 2012 Jan 2. J Exp Med. 2012. PMID: 22213804 Free PMC article.
High level of PD-1 expression on hepatitis C virus (HCV)-specific CD8+ and CD4+ T cells during acute HCV infection, irrespective of clinical outcome.
Kasprowicz V, Schulze Zur Wiesch J, Kuntzen T, Nolan BE, Longworth S, Berical A, Blum J, McMahon C, Reyor LL, Elias N, Kwok WW, McGovern BG, Freeman G, Chung RT, Klenerman P, Lewis-Ximenez L, Walker BD, Allen TM, Kim AY, Lauer GM. Kasprowicz V, et al. Among authors: kwok ww. J Virol. 2008 Mar;82(6):3154-60. doi: 10.1128/JVI.02474-07. Epub 2007 Dec 26. J Virol. 2008. PMID: 18160439 Free PMC article.
Broadly directed SARS-CoV-2-specific CD4+ T cell response includes frequently detected peptide specificities within the membrane and nucleoprotein in patients with acute and resolved COVID-19.
Heide J, Schulte S, Kohsar M, Brehm TT, Herrmann M, Karsten H, Marget M, Peine S, Johansson AM, Sette A, Lütgehetmann M, Kwok WW, Sidney J, Schulze Zur Wiesch J. Heide J, et al. Among authors: kwok ww. PLoS Pathog. 2021 Sep 16;17(9):e1009842. doi: 10.1371/journal.ppat.1009842. eCollection 2021 Sep. PLoS Pathog. 2021. PMID: 34529740 Free PMC article.
High and Sustained Ex Vivo Frequency but Altered Phenotype of SARS-CoV-2-Specific CD4+ T-Cells in an Anti-CD20-Treated Patient with Prolonged COVID-19.
Cords L, Knapp M, Woost R, Schulte S, Kummer S, Ackermann C, Beisel C, Peine S, Johansson AM, Kwok WW, Günther T, Fischer N, Wittner M, Addo MM, Huber S, Schulze Zur Wiesch J. Cords L, et al. Among authors: kwok ww. Viruses. 2022 Jun 10;14(6):1265. doi: 10.3390/v14061265. Viruses. 2022. PMID: 35746736 Free PMC article.
Evidence for broad cross-reactivity of the SARS-CoV-2 NSP12-directed CD4+ T-cell response with pre-primed responses directed against common cold coronaviruses.
Westphal T, Mader M, Karsten H, Cords L, Knapp M, Schulte S, Hermanussen L, Peine S, Ditt V, Grifoni A, Addo MM, Huber S, Sette A, Lütgehetmann M, Pischke S, Kwok WW, Sidney J, Schulze Zur Wiesch J. Westphal T, et al. Among authors: kwok ww. Front Immunol. 2023 May 5;14:1182504. doi: 10.3389/fimmu.2023.1182504. eCollection 2023. Front Immunol. 2023. PMID: 37215095 Free PMC article.
268 results